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Alkaloids

Fumitremorgin C

(118974-02-0)
Fumitremorgin C is a tremorgenic mycotoxin isolated from Aspergillus fumigatus. Recent research has recognised fumitremorgin C as a potent and specific inhibitor of the breast cancer resistance protein (BCRP/ABCG2) multidrug transporter. It reverses multidrug resistance mediated by BCRP and increases cytotoxicity of several anticancer agents in vitro.

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Alkaloids exist in nature (mainly plants, but some also exist in animals), a type of nitrogen-containing basic organic compounds, which have alkaloid-like properties. According to the basic structure of alkaloids, it can be divided into about 60 categories. Main types: organic amines, pyrrolidines, pyridines, isoquinolines, indoles, scopolamines, imidazoles, quinazolones, purines, steroids, diterpenes, and others.
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