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Alkaloids

(R)-Nornuciferine

(4846-19-9)
N-Nornuciferine is an aporphine alkaloid in lotus leaf that significantly inhibits CYP2D6 with IC50 and Ki of 3.76 and 2.34 μM, respectively.

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Crebanine

(25127-29-1)
Crebanine, an alkaloid from Stephania venosa, induces G1 arrest and apoptosis in human cancer cells. Crebanine exhibits anti-inflammatory activity via suppressing MAPKs and Akt signaling. Crebanine also possesses antiarrhythmic effect[1][2].

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Alkaloids exist in nature (mainly plants, but some also exist in animals), a type of nitrogen-containing basic organic compounds, which have alkaloid-like properties. According to the basic structure of alkaloids, it can be divided into about 60 categories. Main types: organic amines, pyrrolidines, pyridines, isoquinolines, indoles, scopolamines, imidazoles, quinazolones, purines, steroids, diterpenes, and others.
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