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Home > Natural Products > Alkaloids (Find 491 items)

Alkaloids

Gramine

(87-52-5)
For the preparation of dopamine D2 receptor antagonists, antimalarial drugs, 5-indolyl-Mannich bases, proliferation inhibitors, human mast cell chymase inhibitors, DL-tryptophan, potentially cruciferous Plant antitoxin brassinolide detoxification inhibitor, 3-vinylindole, serotonin 5-HT6 receptor ligand template, selective protein kinase Cδ (PKCδ) negative regulator

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(-)-Vindoline

(2182-14-1)
A novel antitumor agent Vendolin has antibacterial, anti-inflammatory and anti-cancer effects; a monomeric vinblastine, which exhibits anti-mitotic activity by inhibiting the assembly of microtubules.

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(-)-Eburnamonine

(4880-88-0)
Cerebral vasodilatator Vincabonin, also called ivory ketone, is white or light yellow crystalline powder at room temperature. Vinblastine is used as a cerebral vasodilator, which has a more pronounced vasodilation effect than vinblastine, and can promote oxygen consumption and the brain's utilization of glucose. As clinically used to treat ischemic stroke and other diseases caused by cerebrovascular disease, it has great significance in clinical application.

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Pilocarpine hydrochloride

(54-71-7)
(+)-Pilocarpine is a muscarinic M1 and M2 acetylcholine receptor agonist with pKB values of 5 and 3.7, respectively. Systemic administration of (+)-pilocarpine is typically used as an animal model for temporal lobe epilepsy and can mimic the generation of complex partial seizures by producing changes in hippocampal neuron morphology, membrane properties, and synaptic responses.

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(±)-Nornicotine

(5746-86-1)
A metabolite of Nicotine. Can catalyze aqueous aldol reactions Use as standard

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9-Aminocamptothecin

(91421-43-1)
9-Amino Camptothecin is a derivative of Camptothecin (C175150), as antitumor agent. Chinese medicine reference substance

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Dauricine

(524-17-4)
Dauricine, a bisbenzylisoquinoline alkaloid in Asiatic Moonseed Rhizome, possesses anti-inflammatory activity. Dauricine inhibits cell proliferation and invasion, and induces apoptosis by suppressing NF-κB activation in a dose- and time-dependent manner in colon cancer[1].

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Alkaloids exist in nature (mainly plants, but some also exist in animals), a type of nitrogen-containing basic organic compounds, which have alkaloid-like properties. According to the basic structure of alkaloids, it can be divided into about 60 categories. Main types: organic amines, pyrrolidines, pyridines, isoquinolines, indoles, scopolamines, imidazoles, quinazolones, purines, steroids, diterpenes, and others.
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