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Home > Organic Chemistry > Amides (Find 150 items)
The amide functional group is crucial in pharmaceuticals, polymers, and bioactive compounds. In biochemistry, the peptide amide bond links amino acids into proteins. Lysergic acid amide, an ergoline alkaloid from plant seeds, shows psychoactive properties under study. Explore more information on Amides including the CAS Numbers, properties, materials, and products from suppliers listed on ECHEMI.

3-(4-Chlorophenyl)-N-(3-methoxyphenyl)-2-propenamide

(472981-92-3)
SB-366791 is a potent , competitive and selective vanilloid receptor (VR1/TRPV1) antagonist with IC50 of 5.7±1.2 nMtarget: VR1/TRPV1IC 50: 5.7±1.2 nM [1] SB-366791 produced a concentration-dependent inhibition of the response to capsaicin with an apparent pKb of 7.74±0.08. Schild analysis indicated a competitive mechanism of action with a pA2 of 7.71.[1] SB-366791 showed a concentration-dependent potentiation of pH 5-induced 45Ca2+uptake in CHO cells expressing rat TRPV1 but not in untra

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Compounds containing amide bonds are called amides. Amides can be regarded as nitrogen-containing derivatives of carboxylic acids, as well as derivatives of ammonia or amines. Amides can be divided into amides, imides, lactams and N-substituted amides according to their structure. It is mainly used as an industrial solvent, used in the production of vitamins and hormones in the pharmaceutical industry, and also used in the manufacture of insecticidal amidine. In organic reactions, dimethylformamide is not only widely used as a solvent for the reaction, but also an important intermediate in organic synthesis.

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Organic compounds made from a carbonyl group (C=O) connected with a nitrogen atom are amides. The amine or ammonia replaces the hydroxyl group of carboxylic acids and they are derived from them. The versatility and reactivity of this group make it pivotal in several chemical industries.

The simplest amide, acetamide is a notable amide, which is used as a solvent and a plasticizer in the polymer industries. Formamide is another important compound that is used as a solvent, and to make pharmaceuticals.

The applications of amides are as follows:

● Pharmaceuticals: Serving as intermediates in drug synthesis.

● Agriculture: Used in the formulation of pesticides and herbicides.

● Polymers: It is also part of those involved in producing nylon and other synthetic fibers.

● Solvents: Employed in industrial cleaning and chemical reactions.

● Textile Industry: For dyeing and finishing applications.

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