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Home > Active Pharmaceutical Ingredients > Antiallergic Drugs (Find 12 items)

Antiallergic Drugs

Promethazine hydrochloride

(58-33-3)
Promethazine is a first generation histamine H1 receptor antagonist (Ki = 2.6 nM) whose antihistamine activity has been reported in guinea pigs and mice at ED50 values of 0.43 and 5.9 mg/kg, respectively.Promethazine can penetrate the CNS, depressing central H1 receptor activity, which may relate to its sedative properties, and can also inhibit muscarinic acetylcholine receptors (Ki = 22 nM). Furthermore, 32 mg/kg promethazine demonstrates antiemetic effects in ferret models of motion sickness o

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Pemirolast potassium

(100299-08-9)
Pemirolast potassium (BMY 26517) is a histamine H1 antagonist and mast cell stabilizer that acts as an antiallergic agent This product is a new type of mast cell membrane stabilizer, which is jointly developed by Bumai-Squibb and Tokyo Tanabe Pharmaceutical Company to inhibit the release of allergic mediators caused by antigens.

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Pheniramine maleate

(132-20-7)
Used medicinally as an antihistaminic (merck).

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Piperidine, 4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methyl-, hydrochloride, hydrate (2:2:3)

(41354-29-4)
Cyproheptadine is a first-generation antihistamine with additional anticholinergic, antiserotonergic, and local anesthetic properties. Cyproheptadine is a 5-HT2/5-HT1C serotonin receptor antagonist; H1 histamine receptor antagonist; antipruritic.

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Pyrilamine maleate

(59-33-6)
A histamine H1 receptor antagonist

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An allergic reaction is an allergic reaction, which refers to tissue damage or physiological dysfunction caused by the body being stimulated by antigenic substances, and is an immunopathological injury process. Drugs for preventing and treating allergic diseases caused by various antigenic substances (such as bacteria, viruses, parasites, pollen, etc.) are anti-allergic drugs. According to the different mechanism of action, it can be divided into: antihistamine drugs, allergic reaction mediator release drugs, histamine desensitizers, leukotriene receptor antagonists, drugs that inhibit antigen-antibody reactions, and improve or control allergic symptoms Medicines, etc. The "ECHEMI Antiallergic Drugs" list mainly supplies APIs for such drugs.
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