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Home > Active Pharmaceutical Ingredients > Antiallergic Drugs (Find 103 items)

Antiallergic Drugs

Ibudilast

(50847-11-5)
Inhibitors of phosphodiesterase 4 (PDE4), which catalyzes the hydrolysis of cAMP, have potential applications in a variety of diseases, including asthma. Ibudilast is an inhibitor of PDE4 (IC50 = 54-239 nM) that, at higher doses, also inhibits PDE3 and PDE5 (IC50 = 1,600-3,510 nM). Through this action, it suppresses the elaboration of mediators involved in asthma and inflammation.[Cayman Chemical]

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Ketotifen fumarate

(34580-14-8)
Antiasthmatic; antiallergic.Antihistamines, antiasthmatic drugs, used to prevent and treat bronchitis and asthma

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Diphenhydramine hydrochloride

(147-24-0)
H1-Histamine receptor antagonist. Antihistaminic; sedative, hypnotic 1) Antihistamine has the effect of competing with histamine released from tissues for H1 receptors on effector cells, thereby preventing allergic reactions. (2) Inhibition of central nervous system activity causes sedative and hypnotic effects (3) Strengthening of antitussives Function (4) It also has anti-vertigo and anti-tremor paralysis effects

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Chlorpheniramine maleate

(113-92-8)
An antagonist of the histamine H1-receptor The antihistamine effect of this product is better than diphenhydramine and promethazine, the dosage is small, and the side effects are light. It is used for urticaria, vasodilation rhinitis, colds, asthma, rhinitis, contact dermatitis, and also used for allergies, insect bites and motion sickness caused by drugs and food. Antihistamines. Similar to clodromic, brompheniramine is also an antihistamine. The production method of bromopheniramine is simila

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Disodium cromoglycate

(15826-37-6)
Chromone complex which blocks mast cell degranulation This product is an anti-allergic drug. It has a good effect on allergic asthma. It can still be used for allergic rhinitis or ulcerative colitis.

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Azelastine hydrochloride

(79307-93-0)
Orally active H1-hystamine receptor antagonist. Antihistaminic Pharmacological effects: Azelastine hydrochloride and its main metabolites are histamine H1 receptor antagonists, which have antihistamine effects. 2. Toxicological research: Genotoxicity: Ames test, DNA damage repair test, mouse lymphocyte positive mutation test, mouse micronucleus test and rat bone marrow chromosome aberration test have not found genetic toxicity.

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Azelastine

(58581-89-8)
anesthetic, anticonvulsant;Used for the treatment of bronchial asthma and nasal allergies; antihistamines; used as antihistamines

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Amlexanox

(68302-57-8)
Inhibits release of allergic mediators from mast cells. Antiallergic; antiasthmaticIt has histamine free reaction inhibitory effect, leukotriene production inhibitory effect and anti-leukotriene effect, resulting in anti-asthma effects. For the treatment of bronchial asthma and allergic rhinitis. Used to treat oral ulcers Antihistamines have a high degree of selectivity for peripheral nerve H1 receptors, a strong effect and a long time. Used for allergic arthritis and allergic rhinitis. Nationa

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Dipicrylamine

(131-73-7)
Reagent for gravimetric determination of potassium.

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An allergic reaction is an allergic reaction, which refers to tissue damage or physiological dysfunction caused by the body being stimulated by antigenic substances, and is an immunopathological injury process. Drugs for preventing and treating allergic diseases caused by various antigenic substances (such as bacteria, viruses, parasites, pollen, etc.) are anti-allergic drugs. According to the different mechanism of action, it can be divided into: antihistamine drugs, allergic reaction mediator release drugs, histamine desensitizers, leukotriene receptor antagonists, drugs that inhibit antigen-antibody reactions, and improve or control allergic symptoms Medicines, etc. The "ECHEMI Antiallergic Drugs" list mainly supplies APIs for such drugs.
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