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Home > Active Pharmaceutical Ingredients > Antiallergic Drugs (Find 103 items)

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Antiallergic Drugs

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Antiallergic Drugs

Epinastine

(80012-43-7)
Epinastine(WAL801) is an antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis.Target: Histamine ReceptorEpinastine shows a high affinity to H1-receptors in receptor binding studies in the guinea pig ileum. Epinastine inhibits histamine-induced reactions in the skin or the lung of rats, dogs and guinea pigs [1]. Epinastine is able to displace specific [3H]NC-5Z binding at low concentrations in the locust nervous tissue. Epinastine binds to the

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Dimenhydrinate

(523-87-5)
An antihistamine with antiemetic properties used to prevent nausea and motion sicknes composed of two drugs 8-Chlorotheophylline (C411440) and Diphenhydramine (D486900). Motion sickness medicine; suitable for nausea, vomiting, dizziness caused by motion sickness, pregnancy, radiation therapy, post-operation, etc.

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azelastine hydrochloride

(153408-28-7)
Orally active H1-hystamine receptor antagonist. Antihistaminic.

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azelastine hydrochloride

(153408-27-6)
Orally active H1-hystamine receptor antagonist. Antihistaminic.

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(±)-Doxylamine

(469-21-6)
Antihistaminic.

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Clemastine fumarate

(14976-57-9)
Clemastine is a selective histamine H1 receptor antagonist (Ki = 0.26 nM) that also displays high affinity for muscarinic receptors (Ki = 16 nM). It has also recently been identified as a positive allosteric modulator of P2X7 receptor signaling. Clemastine has long been used to inhibit histamine-induced bronchoconstriction in asthma and airway hyperresponsive studies.

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Ebastine

(90729-43-4)
A nonsedating type histamine H1-receptor antagonist. Its antihistamine activity is competitive at low concentrations and non-competitive at high concentrations. It is used for allergic diseases, including allergic rhinitis in children, perennial rhinitis in adults, seasonal rhinitis, hay fever and chronic urticaria. Used as an anti-histamine

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Clemastine

(15686-51-8)
Antihistaminic.

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Donormil

(562-10-7)
antihistaminic, hypnotic

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Epinastine hydrochloride

(108929-04-0)
A tetracyclic, non-sedating histamine H1 receptor antagonist. Antihistaminic.

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An allergic reaction is an allergic reaction, which refers to tissue damage or physiological dysfunction caused by the body being stimulated by antigenic substances, and is an immunopathological injury process. Drugs for preventing and treating allergic diseases caused by various antigenic substances (such as bacteria, viruses, parasites, pollen, etc.) are anti-allergic drugs. According to the different mechanism of action, it can be divided into: antihistamine drugs, allergic reaction mediator release drugs, histamine desensitizers, leukotriene receptor antagonists, drugs that inhibit antigen-antibody reactions, and improve or control allergic symptoms Medicines, etc. The "ECHEMI Antiallergic Drugs" list mainly supplies APIs for such drugs.

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