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Home > Active Pharmaceutical Ingredients > Antiallergic Drugs (Find 103 items)

Antiallergic Drugs

Meclizine

(569-65-3)
Used as surfactant, penetrating agent in printing and dyeing industry

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Acrivastine

(87848-99-5)
Competitive H1 receptor antagonist. Used for allergic rhinitis, hay fever, chronic primary urticaria, skin scratches, parasympathetic urticaria, specific air-cooled urticaria, etc.

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Tranilast

(53902-12-8)
Tranilast is a compound that exhibits anti-inflammatory and immunomodulatory effects by inhibiting lipid mediator and cytokine release from inflammatory cells and interfering with PDGF- and TGF-β1-induced proliferation and migration of vascular medial smooth muscle cells. Tranilast suppresses production of prostaglandin D2 (IC50 = 0.1 mM), prostaglandin E2 (IC50 = ~1-20 μM), thromboxane B2 (IC50 = ~10-50 μM), TGF-β1 (IC50 = ~100-200 μM), and interleukin-8 (IC50 = ~100 μM) in in vitro models as w

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Piperidine, 4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methyl-, hydrochloride, hydrate (2:2:3)

(41354-29-4)
Cyproheptadine is a first-generation antihistamine with additional anticholinergic, antiserotonergic, and local anesthetic properties. Cyproheptadine is a 5-HT2/5-HT1C serotonin receptor antagonist; H1 histamine receptor antagonist; antipruritic.

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Pyrilamine maleate

(59-33-6)
A histamine H1 receptor antagonist

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An allergic reaction is an allergic reaction, which refers to tissue damage or physiological dysfunction caused by the body being stimulated by antigenic substances, and is an immunopathological injury process. Drugs for preventing and treating allergic diseases caused by various antigenic substances (such as bacteria, viruses, parasites, pollen, etc.) are anti-allergic drugs. According to the different mechanism of action, it can be divided into: antihistamine drugs, allergic reaction mediator release drugs, histamine desensitizers, leukotriene receptor antagonists, drugs that inhibit antigen-antibody reactions, and improve or control allergic symptoms Medicines, etc. The "ECHEMI Antiallergic Drugs" list mainly supplies APIs for such drugs.
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