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Home > Active Pharmaceutical Ingredients > Antiparasitic Drugs (Find 11 items)

Antiparasitic Drugs

Dehydroemetine

(4914-30-1)
The synthetic racemic derivative of the plant alkaloid emetine. Formulated as the hydrochloride for intramuscular administration. Like the parent compound, emetine, it inhibits E. histolytica at concentrations of 1–10 mg/L in vitro, but it is more active than the parent in animal models. Drugresistance in E. histolytica is rare.
No human pharmacokinetic data are available. A halflife of 2 days, compared with 5 days for emetine, has been reported. There is selective tissue binding and accumu

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Parasitic diseases can be divided into protozoan diseases and helminthiasis. Protozoan diseases include malaria, amoebiasis, leishmaniasis, etc., helminthiasis includes flukes, filariasis and nematodes, etc. Therefore, antiparasitic drugs can be divided into antiprotozoal drugs and antihelminthic drugs. The "ECHEMI Antiparasitic Drugs" list mainly supplies APIs for such drugs.
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