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Home > Active Pharmaceutical Ingredients > Antipyretic Analgesics (Find 9 items)

Antipyretic Analgesics

Chlorogenic acid

(327-97-9)
An antioxidant, also slows the release of glucose into the bloodstream after a meal.Chlorogenic Acid is an analog of caffeic acid that displays antioxidant, analgesic, antipyretic and chemopreventive activity. Chlorogenic acid inhibits Bcr-Abl(the fusion protein of Bcr and c-Abl) tyrosine kinase and triggers MAP kinases p38-dependent apoptosis.

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Celecoxib

(169590-42-5)
A selective cyclooxygenase-2 (COX-2) inhibitor. Anti-inflammatory.It is used to treat arthritis and has anti-inflammatory and analgesic effects, and relieve the symptoms and signs of osteoarthritis and rheumatoid arthritis. Treatment of arthritis medicine. Used for symptomatic treatment of osteoarthritis and rheumatoid arthritis

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Carprofen

(53716-49-7)
Carprofen is a non-steroidal anti-inflammatory drug (NSAID) commonly used in animals to combat pain and inflammation, particularly as associated with osteoarthritis. Like many NSAIDs, carprofen inhibits both cyclooxygenases COX-1 and COX-2 (IC50s = 22.3 and 3.9 μM, respectively). It also inhibits fatty acid amide hydrolase (IC50 = 74 μM), blocking the metabolism of the cannabinoid receptor ligand, arachidonoyl ethanolamide .

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Crassicauline A

(79592-91-9)
3-Deoxyyunaconitine is a metabolite of Aconitine (A189875), a neurotoxin that binds, activates tetrodotoxin-sensitive Na+ channels and prolongs the opening of the sodium-ion channel by suppressing conformational changes.

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Clavulanic Acid Methyl Ester

(57943-82-5)

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Antipyretic Analgesics refer to drugs that can restore the body temperature of fever patients to normal, but have no effect on the body temperature of normal people. Such drugs also have moderate analgesic effects, but their strength is not as strong as morphine and its synthetic substitutes. Commonly used Antipyretic Analgesics can be divided into salicylic acid, aniline and pyrazolone according to their chemical structure. The "ECHEMI Antipyretic Analgesics" list mainly supplies APIs for such drugs.
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