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Home > Active Pharmaceutical Ingredients > Antipyretic Analgesics (Find 165 items)

Antipyretic Analgesics

Dipyrone

(68-89-3)
Dipyrone is a non-steroidal anti-inflammatory drug that, when coadministered with morphine, potentiates its antinociceptive action and delays the development of tolerance. Dipyrone is a relatively selective inhibitor of cyclooxygenase-3 (COX-3), with lower activity against COX-1 and no activity against COX-2. Dipyrone blocks PGE2-induced hyperalgesia in several models.

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Indomethacin

(53-86-1)
antiinflammatory, antipyretic, analgesic.The product has anti-inflammatory and antipyretic effects, and is mainly used for rheumatoid arthritis, ankylosing spondylitis, osteoarthritis, etc., which are not easy to tolerate or have no significant effect on salicylic acid drugs. Uses are non-hormonal anti-inflammatory analgesics. Uses are cyclooxygenase (COX) inhibitors, which selectively inhibit COX-1; block the biosynthesis of prostate cord. It has anti-inflammatory and antipyretic effects in med

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Salicylamide

(65-45-2)
The main medical applications of salicylamine lie in its analgesic (pain relief) and antipyretic (fever reduction) properties. Similar to its close relative aspirin, salicylamine is used as a non-narcotic analgesic and anti-rheumatic, which can relieve various types of pain and inflammation. In addition, salicylamine has been used in combination with other active ingredients (such as aspirin and caffeine) for over-the-counter painkillers, further expanding its therapeutic application. Salicylamine's versatility goes beyond its medical use. Researchers and industry have explored the compound's potential in other areas, including its use as a chemical intermediate for synthesizing more complex organic molecules and its use in specialized industrial processes. The unique physicochemical properties of salicylamide, such as sublimation behavior and dissolution properties, have also generated interest in its potential uses in various technical and engineering applications. As researchers and medical professionals continue to study the properties and potential applications of salicylamine, this versatile compound is likely to maintain its relevance in fields such as pharmaceuticals, chemistry, and more, contributing to the advancement of human health and scientific knowledge. In pharmacology, salicylamine is known for its excellent anti-inflammatory, analgesic and antipyretic properties. Its mechanism of action mainly involves inhibiting the synthesis of prostaglandins, a body substance that plays a key role in pain and inflammatory responses. For this reason, salicylamine is commonly used to treat headaches, muscle pain, arthritis, and fever caused by colds and flu. In addition, salicylamine also shows certain antibacterial and antifungal activity, which makes it potential for topical application in the treatment of skin infections and inflammation. In some cases, it may be used as an alternative to antibiotics, reducing the risk of over-dependence on antibiotics. In the medical field, salicylamine is used as an active ingredient in over-the-counter and prescription drugs, such as non-steroidal anti-inflammatory drugs and certain antimalarial drugs. Because it is less irritating to the gastrointestinal tract, salicylamine may be a better option for patients who cannot tolerate other NSaids, such as aspirin. However, it is important to note that salicylamine may also cause some side effects, such as nausea, stomach upset, or allergic reactions. Therefore, when using any product containing salicylamine, you should follow the advice of your doctor or pharmacist and be aware of possible adverse reactions. Salicylamine has become an important molecule in the pharmaceutical industry due to its unique pharmacological properties, wide range of therapeutic applications and relatively low side effects. With the deepening of scientific research, we may find more new ways to use salicylamine to treat various diseases.

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Mefenamic acid

(61-68-7)
Anti-inflammatory; analgesic.

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Flurbiprofen

(5104-49-4)
antiinflammatory, analgesic

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(-)-Flurbiprofen

(51543-40-9)
(R)-2-Flurbiprofen is the R-isomer of Flurbiprofen (F598700), an anti-inflammatory used as an analgesic.

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Phenylbutazone

(50-33-9)
Phenylbutazone, a nonsteroidal anti-inflammatory drug, is an efficient reducing cofactor for the peroxidase activity of COX. Phenylbutazone-dependent inactivation of COX and prostacyclin synthase is markedly increased in the presence of 100 μM hydrogen peroxide with half-maximal effects at Phenylbutazone concentrations of 100 and 25 μM for COX and prostacyclin synthase, respectively.

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Flunixin meglumine

(42461-84-7)
1. Dental carries prophylactic
2. Cyclooxigenase inhibitor. Anti-inflammatory; analgesic; antipyretic.

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Sumatriptan

(103628-46-2)
Serotonin 5HT1 receptor agonist; treatment of migraine.

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Antipyretic Analgesics refer to drugs that can restore the body temperature of fever patients to normal, but have no effect on the body temperature of normal people. Such drugs also have moderate analgesic effects, but their strength is not as strong as morphine and its synthetic substitutes. Commonly used Antipyretic Analgesics can be divided into salicylic acid, aniline and pyrazolone according to their chemical structure. The "ECHEMI Antipyretic Analgesics" list mainly supplies APIs for such drugs.
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