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Home > Organic Chemistry > Arsenicals (Find 56 items)

Arsenicals

Phenol, 2-amino-4-arsinyl-, hydrochloride (1:1)

(538-03-4)
In 1930, the oxidised compound Oxophenarsine, containing an As=O unit, was identified as the active ingredient and was later marketed under the trade name Mapharsen. Mapharsen was used until the 1940s when it was replaced by Penicillin. Mapharsen was actually synthesised in Ehrlich’s laboratory as compound number 5, but it was believed to be too toxic for any clinical application .
Generally, the use of arsenic-based drugs has ceased, especially as a result of the development of Penicillin.

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Melarsoprol

(494-79-1)
Melarsoprol is a drug used for the treatment of African trypanosomes, a sleeping sickness in humans, a disease that is typically fatal without chemotherapy.

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Tetramethylarsonium iodide

(5814-20-0)
Tetramethylarsonium Iodide is an organoarsenic compound found in marine organisms. Tetramethylarsonium Iodide exhibited very low cytotoxicity towards mammalian cells.

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Thoron (reagent)

(132-33-2)

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Arsenic chloride (AsCl3)

(7784-34-1)
In the ceramic industry; in syntheses of chlorine-contg arsenicals, e.g., chloro derivatives of arsine.

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Arsenicals is a feed additive. Beginning in the 1950s, the commonly used arsenic preparations include p-aminophenylarsinic acid and its sodium salt and 3-nitro-4-hydroxyphenylarsinic acid, among which p-aminophenylarsinic acid is widely used in China. Organic arsenic preparations not only play a nutritional role in supplementing the necessary trace element arsenic, but also have important antibacterial effects, such as inhibiting the growth and reproduction of harmful bacteria in the intestinal tract and preventing dysentery.
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