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Biological Response Modifiers
Biological Response Modifiers
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An aminopeptidase inhibitor used in combination with chemotherapeutics for the maintenance and enhancement of complete remission of acute non-lymphocytic leukemia in adults.
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Bis-tris propane
(64431-96-5)
Bis-tris propane, or 1,3-bis(tris(hydroxymethyl)methylamino)propane, is a chemical substance that is used in buffer solutions. It is a white to off-white crystalline powder that is soluble in water. It has a wide buffering range, from 6 to 9.5 due to its two pKa values which are close in value. This buffer is primarily used in biochemistry and molecular biology.
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Biological response modifiers (BRM), also known as biological regulators, is a new term for immunotherapeutics. Any substance or method that directly or indirectly enhances the body's anti-tumor effect through the immune system and has a therapeutic effect on the tumor can be called a biological response modifier. Biological regulators have multiple functions and uses. It can enhance the body's anti-tumor function, induce tumor cells to differentiate and mature into normal cells; reduce the immunosuppressive effect, enhance the body's tolerance to toxic substances and directly enhance the body's defense capabilities, promote early recovery of the disease; Radiation therapy and surgical treatment have a curative effect on tumors and reduce their side effects.