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Home > Biochemical Engineering > Biological Response Modifiers (Find 15 items)

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Biological Response Modifiers

Phytohemagglutinins

(9008-97-3)
PHA is a mitogen. In vitro, it can stimulate the transformation of small lymphocytes into immunologically active lymphocytes and promote their division. The transformed lymphocytes can secrete various lymphokines. 1. The transformation effect of PHA on peripheral blood lymphocytes. Peripheral blood lymphocytes are cultured with PHA in vitro to transform small lymphocytes into lymphoblasts. 2. PHA stimulates lymphocyte mitosis. 3. PHA can enhance the rosette rate of lymphocytes and can be used to

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Tremella Polysaccharide

(9075-53-0)
Clinically, chemotherapy drugs are used to treat primary lung cancer and squamous cell carcinoma with an effective rate of 80%. For leukemia patients, it can reduce bleeding and infection, alleviate certain adverse reactions of chemotherapy, and prolong the survival time of patients.

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Polyinosinic acid-polycytidylic acid s...

(42424-50-0)
TLR3 recognizes double-stranded RNA and is a major effector of the immune response against viral pathogens. Polyinosinic–polycytidylic acid (Poly(I) • Poly(C)) is a double-stranded homopolymer used as a model RNA to study cell signaling at the level of TLR3. Poly(IC) is a TRIF-dependent toll-like receptor-3 (TLR3) ligand.

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Biological response modifiers (BRM), also known as biological regulators, is a new term for immunotherapeutics. Any substance or method that directly or indirectly enhances the body's anti-tumor effect through the immune system and has a therapeutic effect on the tumor can be called a biological response modifier. Biological regulators have multiple functions and uses. It can enhance the body's anti-tumor function, induce tumor cells to differentiate and mature into normal cells; reduce the immunosuppressive effect, enhance the body's tolerance to toxic substances and directly enhance the body's defense capabilities, promote early recovery of the disease; Radiation therapy and surgical treatment have a curative effect on tumors and reduce their side effects.
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