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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates (Find 652 items)
The quality of pharmaceutical intermediates plays a crucial role in the efficacy and safety of the final drug. Our authorized vendors offer outstanding bulk drug intermediates, the very raw materials for the pharmaceutical production. Explore specific product information, such as CAS numbers, characteristics, and technical data, to improve production efficiency during the drug production process.

Benzyl 3-aminobenzoate hydrochloride

(153243-86-8)

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Bromo(trioctyl)stannane

(3091-29-0)

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Benzoate anion

(766-76-7)
The main components of Benzoate anion are benzoic acid and its derivatives. It has excellent emulsification and dispersion, can effectively reduce the surface tension, and is widely used in the field of pearl gloss agent, emulsion and so on. In addition, benzoic acid surfactants also have the characteristics of antistatic, anti-corrosion, penetration, etc., and are widely used in electronics, metals, engineering and other industries. Benzoate anion is a negatively charged surfactant that is characterized by good cleaning and emulsification capabilities, the ability to stabilize liquid foam, and the effect of reducing surface tension. Anionic surfactants are widely used in various fields such as detergents, concentrates and emulsifiers. Benzoate anion and its sodium salts have no bactericidal and bacteriostatic effects in acidic media, but in slightly acidic or neutral media, benzoate anion will ionize and acidize, inhibit the respiratory enzyme system activity of microbial cells, and thus play a role in bactericidal and antiseptic. Therefore, benzoate anion is widely used as a preservative for food, feed, latex, toothpaste, and cosmetics to prevent product deterioration and extend shelf life. Benzoate anion has antibacterial and anti-inflammatory effects and is therefore used as a pharmaceutical intermediate to synthesize many important drugs such as antibiotics, anti-inflammatory drugs, aspirin, ibuprofen, etc. Benzoate anion can react with other compounds to produce a variety of organic compounds, which have excellent physical and chemical properties, and are widely used in the preparation of fragrances, coatings, dyes and polymer materials. Benzoate anion can be used for seed treatment to improve the speed and efficiency of seed germination. Soaking the seeds in an aqueous solution containing benzoate anion can promote water absorption and accelerate seed growth, thus increasing the productivity and yield of the plant. Benzoate anion can inhibit the activity of tyrosinase, thereby reducing the synthesis of melanin, to achieve whitening effect. Therefore, benzoate anion is often used in whitening products such as whitening creams and whitening serums. Benzoate anion can regulate the pH of the skin, maintain the normal pH of the skin, and maintain the health of the skin.

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Butyric acid

(107-92-6)
A colorless liquid with a penetrating and unpleasant odor.

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Butanediol

(25265-75-2)
Butanediols are not used extensively commercially, but there is considerable interest in them as intermediates for polyester resins. Because of its low toxicity, the 1,3-isomer, has been proposed for cosmetic and pharmaceutical applications.

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Butanedione

(431-03-8)
Diacetyl (2,3-butanedione) is a naturally occurring product and can be found in numerous foods such as butter, milk, cheese, smoked or roasted meats, breads, fruits, vegetables, coffee, beer, and wine. Diacetyl is synthesized to be used as a food additive to impart a buttery flavor and has been designated as a generally recognized as safe (GRAS) substance with low acute toxicity (FDA, 1980). Desirable flavor concentrations in food are approximately 0.05–5.0 ppm and above that range it imparts a

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Bis(2,2,6,6-tetramethyl-4-piperidyl) sebacate

(52829-07-9)
Used in polypropylene, high-density polyethylene unsaturated resin, polyurethane, polystyrene and ABS resin, its light stabilizing effect is better than the commonly used light stabilizer

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Butanal

(123-72-8)
n-Butyraldehyde is used to make rubberaccelerators, synthetic resins, and plasticizers;and as a solvent. Chiefly in the manufacture of rubber accelerators, synthetic resins, solvents, plasticizers.

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Barbituric acid

(67-52-7)
Barbituric acid is a parent compound of barbiturate drugs. Unsubstituted barbituric acid has no hypnotic properties.

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Bulk drug intermediates are the drugs used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API.

More Information

Intermediates are unavoidable products of chemical reactions and are widely used in pharmaceuticals, materials, chemicals, and other industries.

In the pharmaceutical industry, an active pharmaceutical ingredient (API) is a product of a synthesis process that has been completed and is used in the manufacture of bulk drugs and intermediates are some chemical raw materials or chemical products used in the synthesis process of APIs.

The application industries of pharmaceutical intermediates mainly include antibiotics, anticancer drugs, cardiovascular drugs, neurological drugs, hormone drugs, and immunosuppression.

Functions of intermediates

Intermediates serve a variety of responsibilities in the drug production process.

● They can serve as a link between the API and the finished medicine. The drug production process can be broken down into multiple steps using intermediates, each requiring a different chemical.

● They can modify reaction conditions and synthesis pathways, increasing drug synthesis efficiency and yields.

● They can be employed to modify the purification, crystallization, and solid characteristics of medicines.

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