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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates (Find 652 items)
The quality of pharmaceutical intermediates plays a crucial role in the efficacy and safety of the final drug. Our authorized vendors offer outstanding bulk drug intermediates, the very raw materials for the pharmaceutical production. Explore specific product information, such as CAS numbers, characteristics, and technical data, to improve production efficiency during the drug production process.

Benzyl 3-oxoazetidine-1-carboxylate

(105258-93-3)

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Butyl octanoate

(589-75-3)
ChEBI: An octanoate ester obtained by the formal condensation of the carboxy group of octanoic acid with the hydroxy group of butanol.

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Boisambrene forte

(58567-11-6)
BOISAMBRENE FORTE is not known in nature. It is a colorless liquid, bp0.1 Pa 94 °C, d25 25 0.931, n20 D 1.463–1.467, with a noble woody odor with ambergris nuances. It is prepared by reaction of cyclododecanol with paraformaldehyde/hydrochloric gas to give cyclododecyl chloromethyl ether, which is treated with sodium ethylate. (Ethoxymethoxy)cyclododecane is stable in alkaline media and can be used in perfume compositions for soaps and detergents.

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Bruceantin

(41451-75-6)
Bruceantin(NSC165563) is first isolated from Brucea antidysenterica, a tree used in Ethiopia for the treatment of cancer, and activity was observed against B16 melanoma, colon 38, and L1210 and P388 leukemia in mice.IC50 value:Target: anticancerCell differentiation was induced and c-MYC was down-regulated, suggesting a mechanistic correlation between c-MYC down-regulation and induction of cell differentiation or cell death. Treatment of HL-60 and RPMI 8226 cell lines induced apoptosis, a

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benzofuran-4-carboxylic acid

(166599-84-4)
4-Benzofurancarboxylic Acid is a benzofuran derivative used in the preparation of dual orexin 1 and orexin 2 receptor antagonist which are useful for the treatment of sleep disorders.

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Borate(5-), bis[μ-oxotetraoxodiborato(4-)]-, ammonium hydrogen, hydrate (1:1:4:2), (T-4)-

(12046-04-7)
Mainly used in the manufacture of telecommunications equipment and high-grade glass. Used as metal protective agent, fire retardant, detergent and analytical reagent. It is also used in the synthesis of boride intermediates.

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B-(1-Methyl-1H-indol-2-yl)boronic acid

(191162-40-0)

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Bulk drug intermediates are the drugs used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API.

More Information

Intermediates are unavoidable products of chemical reactions and are widely used in pharmaceuticals, materials, chemicals, and other industries.

In the pharmaceutical industry, an active pharmaceutical ingredient (API) is a product of a synthesis process that has been completed and is used in the manufacture of bulk drugs and intermediates are some chemical raw materials or chemical products used in the synthesis process of APIs.

The application industries of pharmaceutical intermediates mainly include antibiotics, anticancer drugs, cardiovascular drugs, neurological drugs, hormone drugs, and immunosuppression.

Functions of intermediates

Intermediates serve a variety of responsibilities in the drug production process.

● They can serve as a link between the API and the finished medicine. The drug production process can be broken down into multiple steps using intermediates, each requiring a different chemical.

● They can modify reaction conditions and synthesis pathways, increasing drug synthesis efficiency and yields.

● They can be employed to modify the purification, crystallization, and solid characteristics of medicines.

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