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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates (Find 538 items)
The quality of pharmaceutical intermediates plays a crucial role in the efficacy and safety of the final drug. Our authorized vendors offer outstanding bulk drug intermediates, the very raw materials for the pharmaceutical production. Explore specific product information, such as CAS numbers, characteristics, and technical data, to improve production efficiency during the drug production process.

C3A (70-77)

(63555-63-5)
C3a (70-77) is an octapeptide corresponding to the COOH terminus of C3a, exhibits the specificity and 1 to 2% biologic activities of C3a.

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Colchiceine

(477-27-0)
A metabolite of Colchicine

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cis-1,4-Cyclohexanediol

(931-71-5)
cis-1,4-Cyclohexanediol is an metabolite of side-chain of candesartan cilexetil (C175580), on digoxin-induced arrhythmias in dogs with congestive heart failure.

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CHROMANE-2-CARBOXYLIC ACID

(51939-71-0)
Chromane-2-carboxylic Acid is used in the synthesis of 4-quinazolinones as Rho kinase inhibitors for application towards glaucoma, hypertension and spinal cord injuries. It is also used in the preparation of chromanyl-benzamidazoles as anti-bacterial compounds.

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Cobimetinib

(934660-93-2)
A potent, selective, orally bioavailable inhibitor of MEK1, a component of the RAS/RAF/MEK/ERK pathway. It inhibits proliferation and stimulates apoptosis in a variety of human tumor cell lines. In preclinical xenograft models, oral administration of XL518 results in sustained inhibition of pERK in tumor tissue, but not brain tissue, leading to tumor growth inhibition and regression at well tolerated doses.

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CID 137031716

(31852-29-6)

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Columbamine

(3621-36-1)
Columbamine is a quaternary isoquinoline alkaloid isolated from Argemone mexicana.

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Bulk drug intermediates are the drugs used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API.

More Information

Intermediates are unavoidable products of chemical reactions and are widely used in pharmaceuticals, materials, chemicals, and other industries.

In the pharmaceutical industry, an active pharmaceutical ingredient (API) is a product of a synthesis process that has been completed and is used in the manufacture of bulk drugs and intermediates are some chemical raw materials or chemical products used in the synthesis process of APIs.

The application industries of pharmaceutical intermediates mainly include antibiotics, anticancer drugs, cardiovascular drugs, neurological drugs, hormone drugs, and immunosuppression.

Functions of intermediates

Intermediates serve a variety of responsibilities in the drug production process.

● They can serve as a link between the API and the finished medicine. The drug production process can be broken down into multiple steps using intermediates, each requiring a different chemical.

● They can modify reaction conditions and synthesis pathways, increasing drug synthesis efficiency and yields.

● They can be employed to modify the purification, crystallization, and solid characteristics of medicines.

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