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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates (Find 518 items)
The quality of pharmaceutical intermediates plays a crucial role in the efficacy and safety of the final drug. Our authorized vendors offer outstanding bulk drug intermediates, the very raw materials for the pharmaceutical production. Explore specific product information, such as CAS numbers, characteristics, and technical data, to improve production efficiency during the drug production process.

Dolomite (CaMg(CO3)2)

(16389-88-1)
Dolomite is a carbonate of calcium and magnesium. It is a mineral of formula CaMg(CO
3
)
2
with a rhombohedral system. It has a density of 2.8 g/cc and hardness of 4 on the Mohs scale.
Dolomite has a vitreous lustre which is between transparent and translucent. It effervesces with hot concentratedh ydrochloric acid (HCl).
A carbonate-rich sedimentary rock of chemical or biological origin contains 50% or more carbonate, of which at least half is in the form of dolomite.

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Dapagliflozin

(461432-26-8)
A sodium-glucose transporter 2 inhibitor.

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Disodium 5'-ribonucleotide

(80702-47-2)

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Dioctyl adipate

(123-79-5)
Primary type of plasticizer for use with resins @ low temp. Plasticizer for synthetic rubbers, nitrocellulose, & ethyl cellulose.

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DMF

(1000612-40-7)

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Diisopropylcarbodiimide

(693-13-0)
Activating reagent used in solid phase peptide synthesis.

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Dimethyl malonate

(108-59-8)
It is used in fragrances and some artificial flavorings .

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Dibutyl maleate

(105-76-0)
1. Used as raw materials for synthetic resins and coatings, also used as impregnants, dispersants, lubricants, etc. in the petroleum industry, textiles, plastics, paper industry, and as plasticizers for polyvinyl chloride resins and methacrylic resins. Maleate is used as an intermediate in organic synthesis mainly for addition reactions on double bonds. For example, the Diels-Alder reaction with butadiene, cyclopentadiene, etc. adds hydrogen, nitrile, thiol, amine, and other active hydrogen-cont

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Diethyl oxalate

(95-92-1)
manufacture of phenobarbital, ethylbenzyl malonate, triethylamine, and similar chemicals, plastics, dyestuff intermediates. Solvent for cellulose esters, perfumes.

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Bulk drug intermediates are the drugs used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API.

More Information

Intermediates are unavoidable products of chemical reactions and are widely used in pharmaceuticals, materials, chemicals, and other industries.

In the pharmaceutical industry, an active pharmaceutical ingredient (API) is a product of a synthesis process that has been completed and is used in the manufacture of bulk drugs and intermediates are some chemical raw materials or chemical products used in the synthesis process of APIs.

The application industries of pharmaceutical intermediates mainly include antibiotics, anticancer drugs, cardiovascular drugs, neurological drugs, hormone drugs, and immunosuppression.

Functions of intermediates

Intermediates serve a variety of responsibilities in the drug production process.

● They can serve as a link between the API and the finished medicine. The drug production process can be broken down into multiple steps using intermediates, each requiring a different chemical.

● They can modify reaction conditions and synthesis pathways, increasing drug synthesis efficiency and yields.

● They can be employed to modify the purification, crystallization, and solid characteristics of medicines.

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