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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates (Find 189 items)
The quality of pharmaceutical intermediates plays a crucial role in the efficacy and safety of the final drug. Our authorized vendors offer outstanding bulk drug intermediates, the very raw materials for the pharmaceutical production. Explore specific product information, such as CAS numbers, characteristics, and technical data, to improve production efficiency during the drug production process.

Ibrutinib

(936563-96-1)
Ibrutinib (PCI-32765) is a selective, irreversible Btk inhibitor with an IC50 of 0.5 nM.

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Iodonium, bis[4-(1,1-dimethylethyl)phenyl]-, chloride

(5421-53-4)

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Indazole

(271-44-3)
white to beige needle-like crystalline powder

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Isoquinoline

(119-65-3)
It can produce medicines and high-efficiency insecticides. After oxidation, it can be made into pyridine carboxylic acid, and its derivatives can be used to make color films and dyes. Used as intermediates for the synthesis of drugs, dyes, pesticides and gas chromatography fixatives. Used in the production of pesticides, medicines, rubber accelerators, color film sensitizers, dyes and other products. Used as raw materials for medicines, dyes, pesticides, anion exchange resins, etc., preservative

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Indole-2-carboxylic acid

(1477-50-5)
• ;Reactant for total synthesis of (±)-dibromophakellin and analogs1• ;Reactant for synthesis of the pyrrolizidine alkaloid (±)-trachelanthamidine2• ;Reactant for stereoselective preparation of renieramycin G analogs3• ;Reactant for preparation of spirooxoindolepyrrolidines via reduction of indole-2-carboxylic acid followed by oxidation, condensation, reduction, amidation and Kharasch radical cyclization4• ;Reactant for Pd-catalyzed cyclization5• ;Reactant for preparation of N,N′-(pentane)diylb

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Isophorone

(78-59-1)
Isophorone is used as a solvent for vinylresins and cellulose esters, and in pesticides. Solvent in some printing inks, paints, lacquers and adhesives.

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Indene

(95-13-6)
Mainly used to produce indene-gumarone resin. The raw material of indene-gumarone resin is the 160-215°C distillate cut from the heavy benzene and light oil fractions, which roughly contains 6% styrene, 4% coumarone, 40% indene, and 4-methylstyrene 5 % And a small amount of xylene, toluene and other compounds, the total amount of resin accounts for 60-70% of the raw materials. Under the action of catalysts such as aluminum chloride, boron fluoride or concentrated sulfuric acid, the indene and co

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Indoline

(496-15-1)
As an indole derivative, Indoline can be used in the preparation of various medicinal compounds such as potential α1-adrenoceptor (α1-AR) antagonists.

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Isophthalic acid

(121-91-5)
Isophthalic acid is an organic compound with the formula C6H4(CO2H)2. This colourless solid is an isomer of phthalic acid and terephthalic acid.

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Indazole-3-carboxylic acid

(4498-67-3)
Indazole-3-carboxylic acid is indole derivatives useful in treatment of pain and inflammation

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Bulk drug intermediates are the drugs used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API.

More Information

Intermediates are unavoidable products of chemical reactions and are widely used in pharmaceuticals, materials, chemicals, and other industries.

In the pharmaceutical industry, an active pharmaceutical ingredient (API) is a product of a synthesis process that has been completed and is used in the manufacture of bulk drugs and intermediates are some chemical raw materials or chemical products used in the synthesis process of APIs.

The application industries of pharmaceutical intermediates mainly include antibiotics, anticancer drugs, cardiovascular drugs, neurological drugs, hormone drugs, and immunosuppression.

Functions of intermediates

Intermediates serve a variety of responsibilities in the drug production process.

● They can serve as a link between the API and the finished medicine. The drug production process can be broken down into multiple steps using intermediates, each requiring a different chemical.

● They can modify reaction conditions and synthesis pathways, increasing drug synthesis efficiency and yields.

● They can be employed to modify the purification, crystallization, and solid characteristics of medicines.

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