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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates (Find 616 items)
The quality of pharmaceutical intermediates plays a crucial role in the efficacy and safety of the final drug. Our authorized vendors offer outstanding bulk drug intermediates, the very raw materials for the pharmaceutical production. Explore specific product information, such as CAS numbers, characteristics, and technical data, to improve production efficiency during the drug production process.

Nicotinamide mononucleotide

(1094-61-7)
A product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation.

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N,O-Bis(trimethylsilyl)acetamide

(10416-59-8)
Powerful silylation reagent for a wide range of functional groups under mild conditions

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N-Methylbenzamide

(613-93-4)
N-Methylbenzamide is a potent phosphodiesterase 10A (PDE10A) inhibitor. N-Methylbenzamide has anti-cancer activity[1][2].

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Nicotinamide riboside

(1341-23-7)
Nicotinamide riboside is a crystal form of Nicotinamide riboside (NR) chloride. Nicotinamide riboside increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities. Nicotinamide riboside is used in dietary supplements[1].

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Nitrapyrin

(1929-82-4)
Colorless or white, crystalline solid with a mild, sweet odor.

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N-Vinyl-2-pyrrolidone

(88-12-0)
A pyrrolidine used for biochemical research

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N,N-Dimethylbenzylamine

(103-83-3)
Intermediate, especially for quaternary ammonium compounds; dehydrohalogenating catalyst; corrosion inhibitor; acid neutralizer; potting compounds; adhesives; cellulose modifier.

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N-(1,1-Dimethylethyl)-2-benzothiazolesulfenamide

(95-31-8)
It can be used as after-effect accelerator of natural rubber, butadiene rubber, isoprene rubber, styrene-butadiene rubber and natural rubber reclaimed rubber. This product has the advantages of excellent scorch resistance and short vulcanization time, that is, there is no danger of scorch at the operating temperature and the promotion effect is strong at the vulcanization temperature, especially the aftereffect in natural rubber is greater. This product needs to be combined with zinc oxide and s

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Nonanoic acid

(112-05-0)
In the production of hydrotropic salts (hydrotropic salts form aqueous solutions which dissolve sparingly soluble substances to a greater extent than water); in the manufacture of lacquers, plastics.

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Bulk drug intermediates are the drugs used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API.

More Information

Intermediates are unavoidable products of chemical reactions and are widely used in pharmaceuticals, materials, chemicals, and other industries.

In the pharmaceutical industry, an active pharmaceutical ingredient (API) is a product of a synthesis process that has been completed and is used in the manufacture of bulk drugs and intermediates are some chemical raw materials or chemical products used in the synthesis process of APIs.

The application industries of pharmaceutical intermediates mainly include antibiotics, anticancer drugs, cardiovascular drugs, neurological drugs, hormone drugs, and immunosuppression.

Functions of intermediates

Intermediates serve a variety of responsibilities in the drug production process.

● They can serve as a link between the API and the finished medicine. The drug production process can be broken down into multiple steps using intermediates, each requiring a different chemical.

● They can modify reaction conditions and synthesis pathways, increasing drug synthesis efficiency and yields.

● They can be employed to modify the purification, crystallization, and solid characteristics of medicines.

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