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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates (Find 573 items)
The quality of pharmaceutical intermediates plays a crucial role in the efficacy and safety of the final drug. Our authorized vendors offer outstanding bulk drug intermediates, the very raw materials for the pharmaceutical production. Explore specific product information, such as CAS numbers, characteristics, and technical data, to improve production efficiency during the drug production process.

Potassium tert-butoxide

(865-47-4)
Usually used for greener amidation of esters.

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p-Bromoacetophenone

(99-90-1)
Possess activity against positive phototaxis of Chlamydomonas cells. A fundamental starting material for organic synthesis. Intermediates of Liquid Crystals

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Potassium phthalimide

(1074-82-4)
Usually used as organocatalyst for the cyanosilylation of various carbonyl compounds under extremely mild conditions,and also used as reagent for the transformation of allyl- and alkyl halides into protected primary amines.

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Pyrroloquinoline quinone

(72909-34-3)

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Pemetrexed

(137281-23-3)
Pemetrexed is a novel antifolate, the Ki values of the pentaglutamate of LY231514 are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively.

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Pentanoic acid, 4-methyl-3-oxo-, methyl ester

(42558-54-3)
Usedfor the synthesis if heterocycles (Furane, Pyrazolone, Chinilone) and building block for pharmaceuticals (reducer of cholesterol). Product Data Sheet

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Pyridoxal 5′-phosphate monohydrate

(41468-25-1)
The active form of vitamin b 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate.

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Bulk drug intermediates are the drugs used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API.

More Information

Intermediates are unavoidable products of chemical reactions and are widely used in pharmaceuticals, materials, chemicals, and other industries.

In the pharmaceutical industry, an active pharmaceutical ingredient (API) is a product of a synthesis process that has been completed and is used in the manufacture of bulk drugs and intermediates are some chemical raw materials or chemical products used in the synthesis process of APIs.

The application industries of pharmaceutical intermediates mainly include antibiotics, anticancer drugs, cardiovascular drugs, neurological drugs, hormone drugs, and immunosuppression.

Functions of intermediates

Intermediates serve a variety of responsibilities in the drug production process.

● They can serve as a link between the API and the finished medicine. The drug production process can be broken down into multiple steps using intermediates, each requiring a different chemical.

● They can modify reaction conditions and synthesis pathways, increasing drug synthesis efficiency and yields.

● They can be employed to modify the purification, crystallization, and solid characteristics of medicines.

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