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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates (Find 34 items)
The quality of pharmaceutical intermediates plays a crucial role in the efficacy and safety of the final drug. Our authorized vendors offer outstanding bulk drug intermediates, the very raw materials for the pharmaceutical production. Explore specific product information, such as CAS numbers, characteristics, and technical data, to improve production efficiency during the drug production process.

Urolithin A

(1143-70-0)
Urolithin A is an intestinal metabolite of ellagic acid with antioxidant and antiproliferative effects; inhibits T24 and Caco-2 cell growth with IC50 values of 43.9 and 49 μM, respectively.

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Urea hydrochloride

(506-89-8)
Urea hydrochloride is nitrogen-release fertilizer. It is starting material for resins and plastics. Condensed with malonic ester to form barbituric acid. Used in the manufacture of paper.

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undecanoic acid

(63400-07-7)

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Urea, N-(3-aminophenyl)-, hydrochloride (1:1)

(59690-88-9)
Used as a reactive dye intermediate, used to prepare yellow to orange dyes, and is a substitute for intermediate aminoacetanilide

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UNII-MGN125FS9D

(1019206-88-2)
Regorafenib monohydrate is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively.

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Uridine 5′-(trihydrogen diphosphate), sodium salt (1:2)

(27821-45-0)

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Umeclidinium bromide

(869113-09-7)
Umeclidinium bromide is a novel mAChR antagonist. The affinity (Ki) of Umeclidinium bromide for the cloned human M1-M5 mAChRs ranges from 0.05 to 0.16 nM.

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Urea, N-(aminoiminomethyl)-, phosphate (1:?)

(17675-60-4)

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Upadacitinib hemihydrate

(2050057-56-0)

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Bulk drug intermediates are the drugs used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API.

More Information

Intermediates are unavoidable products of chemical reactions and are widely used in pharmaceuticals, materials, chemicals, and other industries.

In the pharmaceutical industry, an active pharmaceutical ingredient (API) is a product of a synthesis process that has been completed and is used in the manufacture of bulk drugs and intermediates are some chemical raw materials or chemical products used in the synthesis process of APIs.

The application industries of pharmaceutical intermediates mainly include antibiotics, anticancer drugs, cardiovascular drugs, neurological drugs, hormone drugs, and immunosuppression.

Functions of intermediates

Intermediates serve a variety of responsibilities in the drug production process.

● They can serve as a link between the API and the finished medicine. The drug production process can be broken down into multiple steps using intermediates, each requiring a different chemical.

● They can modify reaction conditions and synthesis pathways, increasing drug synthesis efficiency and yields.

● They can be employed to modify the purification, crystallization, and solid characteristics of medicines.

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