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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates (Find 17017 items)
The quality of pharmaceutical intermediates plays a crucial role in the efficacy and safety of the final drug. Our authorized vendors offer outstanding bulk drug intermediates, the very raw materials for the pharmaceutical production. Explore specific product information, such as CAS numbers, characteristics, and technical data, to improve production efficiency during the drug production process.

Ibrutinib

(936563-96-1)
Ibrutinib (PCI-32765) is a selective, irreversible Btk inhibitor with an IC50 of 0.5 nM.

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2-[(2S)-2-Oxiranylmethyl]-1H-isoindole-1,3(2H)-dione

(161596-47-0)
(S)-N-glycidyl phthalimide is also called S-glycidyl phthalimide. (S)-N-Glycidylphthalimide is an important intermediate for the preparation of rivaroxaban, new antibiotic linezolid, antifungal thiooxazolidinone, and oxazolidinone.

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N-Methyl-1-naphthalenemethanamine

(14489-75-9)
1-Methyl-aminomethyl naphthalene has been used as reagent for the determination of isocyanates in air by UV or fluorescence detection. 1-Methyl-aminomethyl naphthalene has been used in the preparation of key intermediate required for the synthesis of terbinafine.

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4-(4-Aminophenyl)morpholin-3-one

(438056-69-0)
Rivaroxaban intermediate.4-(4-Aminophenyl)morpholin-3-one is a ketone organic substance and can be used as a pharmaceutical intermediate. 4-(4-Aminophenyl)morphin-3-one is used as a reagent for preparing various morpholine-based drugs. Metabolites of rivaroxaban. 4-(4-Aminophenyl)-3-morpholinone is an intermediate of rivaroxaban, an intermediate of rivaroxaban, which is used in adult patients undergoing elective hip or knee replacement surgery to prevent venous thrombosis (VTE). An important int

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(S)-1-Boc-3-hydroxypiperidine

(143900-44-1)
A piperidine derivative with an amine protecting group used in the preparation of biologically active compounds such as antagonists of the human P2X7 receptor and selective irreversible inhibitors for bruton's tyrosine kinase.

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(+)-Pinanediol

(18680-27-8)
(1S,2S,3R,5S)-(+)-2,3-Pinanediol is a bicyclic monoterpene diols that has been shown to induce differentiation of S91 melanoma and PC12 pheochromocytoma cells and thus provide possible therapeutic and sunless tanning use. It is also used in the transformation of isopinocampheol and caryophyllene oxide.

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Linagliptin

(668270-12-0)
A novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes.

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(R)-(-)-3-Aminopiperidine dihydrochloride

(334618-23-4)
(R)-3-Aminopiperidine dihydrochloride, as a chiral compound, is an important intermediate in the synthesis of chemicals and pharmaceuticals. It has important applications in the chemical and pharmaceutical industries. It is a new fine chemical, low-toxic pesticide, and high additive It is an important intermediate for medicine and chemical additives. The pharmaceutical industry is mainly used to synthesize dipeptidyl peptidase IV (DPP-IV) inhibitors, such as troglitin, alogliptin and other diabe

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Bulk drug intermediates are the drugs used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API.

More Information

Intermediates are unavoidable products of chemical reactions and are widely used in pharmaceuticals, materials, chemicals, and other industries.

In the pharmaceutical industry, an active pharmaceutical ingredient (API) is a product of a synthesis process that has been completed and is used in the manufacture of bulk drugs and intermediates are some chemical raw materials or chemical products used in the synthesis process of APIs.

The application industries of pharmaceutical intermediates mainly include antibiotics, anticancer drugs, cardiovascular drugs, neurological drugs, hormone drugs, and immunosuppression.

Functions of intermediates

Intermediates serve a variety of responsibilities in the drug production process.

● They can serve as a link between the API and the finished medicine. The drug production process can be broken down into multiple steps using intermediates, each requiring a different chemical.

● They can modify reaction conditions and synthesis pathways, increasing drug synthesis efficiency and yields.

● They can be employed to modify the purification, crystallization, and solid characteristics of medicines.

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