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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates (Find 17016 items)
The quality of pharmaceutical intermediates plays a crucial role in the efficacy and safety of the final drug. Our authorized vendors offer outstanding bulk drug intermediates, the very raw materials for the pharmaceutical production. Explore specific product information, such as CAS numbers, characteristics, and technical data, to improve production efficiency during the drug production process.

Phenylboronic acid

(98-80-6)
1. Reagent used for• ;Rhodium-catalyzed intramolecular amination1 • ;Pd-catalyzed direct arylation2 • ;Mizoroki-Heck and Suzuki-Miyaura coupling reactions catalyzed by palladium nanoparticles3 • ;Palladium-catalyzed stereoselective Heck-type reaction4 • ;Highly effective Palladium-catalyzed arylation Suzuki-Miyaura cross-coupling in water5 Reagent used in Preparation of• ;Ni(II) pincer complex and Pd(II) pyridoxal hydrazone metallacycles as catalysts for the Suzuki-Miyaura cross-coupling reactio

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Fluorene

(86-73-7)
Fluorene is often used as a precursor to synthesize other fluorene-based compounds and is a raw material for synthesizing medicines, pesticides, dyes, and engineering plastics. Fluorene can be used as a chemical intermediate for the synthesis of polymer free radicals for resins, and is also used to prepare resin products and dyes. It can also be used as a wetting agent, detergent, liquid flash, disinfectant, etc.

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(-)-Amlodipine

(103129-82-4)
(S)-Enantiomer of Amlodipine. A dihydropyridine calcium channel blocker; activity resides mainly in the (-)-isomer.

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Nitrotoluene

(1321-12-6)
Nitrotoluene is formed in 3 isomeric forms. The o-and m-forms are yellow liquids or solids. The p-form is a pale yellow crystalline solid. All have weak aromatic odors. The Odor Thresholds are: 0.05 mg/L (o-isomer); 1.74 ppm (m-isomer).Exists as either a yellow solid crystal or liquid. Melting point 32 to 59°F. Insoluble in water and soluble in alcohol. Denser than water. Toxic by ingestion, inhalation or skin contact. Flash point 223°F. Boiling point 428°F. Produces toxic oxides of n

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Butanediol

(25265-75-2)
Butanediols are not used extensively commercially, but there is considerable interest in them as intermediates for polyester resins. Because of its low toxicity, the 1,3-isomer, has been proposed for cosmetic and pharmaceutical applications.

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Isoquinoline

(119-65-3)
It can produce medicines and high-efficiency insecticides. After oxidation, it can be made into pyridine carboxylic acid, and its derivatives can be used to make color films and dyes. Used as intermediates for the synthesis of drugs, dyes, pesticides and gas chromatography fixatives. Used in the production of pesticides, medicines, rubber accelerators, color film sensitizers, dyes and other products. Used as raw materials for medicines, dyes, pesticides, anion exchange resins, etc., preservative

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Bulk drug intermediates are the drugs used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API.

More Information

Intermediates are unavoidable products of chemical reactions and are widely used in pharmaceuticals, materials, chemicals, and other industries.

In the pharmaceutical industry, an active pharmaceutical ingredient (API) is a product of a synthesis process that has been completed and is used in the manufacture of bulk drugs and intermediates are some chemical raw materials or chemical products used in the synthesis process of APIs.

The application industries of pharmaceutical intermediates mainly include antibiotics, anticancer drugs, cardiovascular drugs, neurological drugs, hormone drugs, and immunosuppression.

Functions of intermediates

Intermediates serve a variety of responsibilities in the drug production process.

● They can serve as a link between the API and the finished medicine. The drug production process can be broken down into multiple steps using intermediates, each requiring a different chemical.

● They can modify reaction conditions and synthesis pathways, increasing drug synthesis efficiency and yields.

● They can be employed to modify the purification, crystallization, and solid characteristics of medicines.

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