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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates (Find 17023 items)
The quality of pharmaceutical intermediates plays a crucial role in the efficacy and safety of the final drug. Our authorized vendors offer outstanding bulk drug intermediates, the very raw materials for the pharmaceutical production. Explore specific product information, such as CAS numbers, characteristics, and technical data, to improve production efficiency during the drug production process.

N-Methylbenzamide

(613-93-4)
N-Methylbenzamide is a potent phosphodiesterase 10A (PDE10A) inhibitor. N-Methylbenzamide has anti-cancer activity[1][2].

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5-Chloroindole

(17422-32-1)
5-Chloroindole is a halo-substituted indole used in the preparation of neurologically active compounds such as atypical antipsychotic agents. 5-Chloroindole has been shown to depress serotonin levels in the brainstem and telencephalon.

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Melamine cyanurate

(37640-57-6)
Environmental-friendly halogen-free inflaming lubricating agent Melamine Cyanurate is a crystalline complex formed between Melamine (M208700) and Cyanuric Acid (C987715), and is unique in that it is a halogen-free flame retardant.

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2-Mercaptopyrimidine

(1450-85-7)
YELLOW POWDERChEBI: Pyrimidine substituted at C-2 by a sulfanyl group.

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Tetraethoxysilane

(78-10-4)
Used for precision casting, as a sand-type adhesive; metal surfaces treated with ethyl silicate can be anti-corrosion and waterproof. Ethyl silicate can be used to infiltrate silicon on the metal surface, and the treatment of optical glass can improve the light transmittance; after complete hydrolysis, extremely fine silicon oxide powder can be used to make phosphor. Ethyl silicate is the raw material of silicone oil, and can also be used to manufacture heat-resistant and chemical-resistant coat

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Cyclopentanone

(120-92-3)
1, Take the n-valeraldehyde and cyclopentanone as raw material, and first go through aldol condensation reaction and further dehydration reaction to obtain pentylene cyclopentanone, then followed by selective catalytic hydrogenation to obtain pentyl cyclopentanone. Pentyl cyclopentanone has strong floral and fruity aroma as well as nuances of jasmine. It can be used in the formulation of daily chemical flavor with the usage amount being less than 20%. IFRA has no restrictions.
2, Take n

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1,4′-Bipiperidine

(4897-50-1)
Reactant for synthesis of: Arylthiadiazole H3 antagonists1 Water-soluble N-mustards as anticancer agents2 Antitubercular drugs3 Vasopressin1b receptor antagonists4 MDR modulators5 Selective Norepinephrine transporter inhibitors6

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1H-Pyrazol-3-amine

(1820-80-0)
Used in the preparation of heterocyclic compounds of pharamaceutical interest

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Bulk drug intermediates are the drugs used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API.

More Information

Intermediates are unavoidable products of chemical reactions and are widely used in pharmaceuticals, materials, chemicals, and other industries.

In the pharmaceutical industry, an active pharmaceutical ingredient (API) is a product of a synthesis process that has been completed and is used in the manufacture of bulk drugs and intermediates are some chemical raw materials or chemical products used in the synthesis process of APIs.

The application industries of pharmaceutical intermediates mainly include antibiotics, anticancer drugs, cardiovascular drugs, neurological drugs, hormone drugs, and immunosuppression.

Functions of intermediates

Intermediates serve a variety of responsibilities in the drug production process.

● They can serve as a link between the API and the finished medicine. The drug production process can be broken down into multiple steps using intermediates, each requiring a different chemical.

● They can modify reaction conditions and synthesis pathways, increasing drug synthesis efficiency and yields.

● They can be employed to modify the purification, crystallization, and solid characteristics of medicines.

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