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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates (Find 17018 items)
The quality of pharmaceutical intermediates plays a crucial role in the efficacy and safety of the final drug. Our authorized vendors offer outstanding bulk drug intermediates, the very raw materials for the pharmaceutical production. Explore specific product information, such as CAS numbers, characteristics, and technical data, to improve production efficiency during the drug production process.

benzofuran-4-carboxylic acid

(166599-84-4)
4-Benzofurancarboxylic Acid is a benzofuran derivative used in the preparation of dual orexin 1 and orexin 2 receptor antagonist which are useful for the treatment of sleep disorders.

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AMMONIUM CHLORIDE-15N

(39466-62-1)
Isotope labelled analogue of Ammonium Chloride, an inorganic compound typically used in flavouring agents and nitrogen source in fertilizers.

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3-(3-Aminophenyl)propionic acid

(1664-54-6)
Used as pharmaceutical intermediates. Used in the production of calcium iodide for diagnosis.

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1-(4-Aminophenyl)-2,2,2-trifluoroethanone

(23516-79-2)
Novel trifluoroacetophenone derivatives as malonyl-CoA decarboxylase inhibitors.

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Chloramphenicol succinate

(3544-94-3)
Chloramphenicol succinate is prepared by acylation of chloramphenicol with succinic anhydride to provide a water soluble pro-drug. Chloramphenicol succinate represents an alternative pro-drug strategy for chloramphenicol that has found a niche in surface antibiotic treatment in surgery. Chloramphenicol succinate is significantly less active than chloramphenicol but acts as a prodrug, forming chloramphenicol in the presence of succinate dehydrogenase.

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2-Deoxy-2-fluoro-L-fucose

(70763-62-1)
Fucose is a deoxyhexose that is present in many organisms. Fucose-containing glycans, generated by fucosyltransferase using GDP-fucose, have roles in cell signaling, cell-cell interactions, and blood properties. 2-deoxy-2-fluoro L-Fucose is a fluorinated fucose analog. It can be metabolized inside the cell to a substrate-based inhibitor of fucosyltransferases. Alternatively, it can be converted in vitro to GDP-2-deoxy-2-fluoro L-fucose, a competitive inhibitor of α1,3-fucosyltransferase V (Ki =

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N-(1-Oxohexadecyl)-L-glutaMic Acid tert-Butyl Este

(536721-25-2)
N-(1-Oxohexadecyl)-L-glutaMic Acid tert-Butyl Ester is a reactant used in the preparation of Liraglutide, a GLP-1R agonist.

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Bulk drug intermediates are the drugs used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API.

More Information

Intermediates are unavoidable products of chemical reactions and are widely used in pharmaceuticals, materials, chemicals, and other industries.

In the pharmaceutical industry, an active pharmaceutical ingredient (API) is a product of a synthesis process that has been completed and is used in the manufacture of bulk drugs and intermediates are some chemical raw materials or chemical products used in the synthesis process of APIs.

The application industries of pharmaceutical intermediates mainly include antibiotics, anticancer drugs, cardiovascular drugs, neurological drugs, hormone drugs, and immunosuppression.

Functions of intermediates

Intermediates serve a variety of responsibilities in the drug production process.

● They can serve as a link between the API and the finished medicine. The drug production process can be broken down into multiple steps using intermediates, each requiring a different chemical.

● They can modify reaction conditions and synthesis pathways, increasing drug synthesis efficiency and yields.

● They can be employed to modify the purification, crystallization, and solid characteristics of medicines.

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