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Chalcones

Phloridzin

(60-81-1)
Sodium-glucose cotransporter 1 (SGLT1) is a high affinity, low capacity transporter abundant in the small intestine, with some expression in the kidney as well. SGLT2 is a low affinity, high capacity transporter in the kidney that accounts for approximately 90% of glucose reabsorption into the blood stream. Selective inhibition of SGLT2 is a potential strategy for reducing plasma glucose levels as a treatment for diabetes. Phlorizin is a natural product, first isolated from the bark of apple tre

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Chalcone, also known as diphenylpropenone, styryl phenyl ketone, benzylidene acetophenone, is a common class of compounds in natural products and has corresponding pharmaceutical activity. The main purpose is to be used as an organic synthesis reagent and indicator.
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