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Home > Active Pharmaceutical Ingredients > Circulatory System Drugs (Find 22 items)

Circulatory System Drugs

Nifedipine

(21829-25-4)
For the management of vasospastic angina, chronic stable angina, hypertension, and Raynaud's phenomenon. May be used as a first line agent for left ventricular hypertrophy and isolated systolic hypertension (long-acting agents).

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Nexavar

(475207-59-1)
Sorafenib Tosylate (Bay 43-9006, Nexavar) is a small molecular inhibitor of VEGFR, PDGFR, c-Raf and B-Raf with IC50s of 18 nM, 10 nM, 3 nM and 15 nM, respectively. Sorafenib Tosylate (Bay 43-9006) is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM, respectively An inhibitor of Flk-1 (VEGFR), PDGFR and Raf kinases.

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Nimodipine

(66085-59-4)
Used as a cerebral vasodilator.A dihydropyridine calcium channel blocker

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Nitrendipine

(39562-70-4)
Nitrendipine is a dihydropyridine calcium channel blocker. Nitrendipine is used in the treatment of primary (essential) hypertension to decrease blood pressure. Antihypertensive.

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Naftopidil

(57149-07-2)
antihypertensive, alpha-blocker, 5HT1a agonist

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Nicardipine

(55985-32-5)
Vasodilator drugs for the treatment of ischemic cerebrovascular diseases and essential hypertension

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Nisoldipine

(63675-72-9)
Labeled Nisoldipine, intended for use as an internal standard for the quantification of Nisoldipine by GC- or LC-mass spectrometry.

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Nicardipine hydrochloride

(54527-84-3)
Nicardipine is a dihydropyridine L-type calcium channel antagonist that displays antihypertensive and antianginal activity. It is reported to inhibit adenosine A1, A2A, and A3 receptors with Ki values of 19.6, 63.8, and 3.25 μM, respectively, and can inhibit cytochrome P450 3A4 catalytic activity with an IC50 value of 0.148 μM. Additionally, nicardipine has been shown to activate transient receptor potential A1 channels, producing an increase in Ca2+ (EC50 = 0.5 μM).

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Circulatory system drugs are about drugs that have the function of regulating the human circulatory system. The circulatory system is a system of body fluids (including blood, lymph and tissue fluids) and pipes through which circulation flows. Circulatory system drugs mainly include cardiovascular system drugs and diuretics. "Circulatory System Drugs" on ECHEMI covers lipid regulating drugs, angina pectoris drugs, calcium channel blockers, anti-congestive heart failure drugs, antihypertensive drugs, antiarrhythmics drugs, anti shock vasoactive drugs, ace inhibitor, peripheral vasodilators, heart failure treatments and drugs, Anti-atherosclerotic drugs, β-adrenergic receptor blockers and other circulatory system drugs, mainly supply raw materials for such drugs.
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