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Home > Active Pharmaceutical Ingredients > Circulatory System Drugs (Find 37 items)

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Circulatory System Drugs

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Circulatory System Drugs

Pitavastatin calcium

(147526-32-7)
Pitavastatin Calcium is a competitive inhibitor of the enzyme HMGCR. Alternate studies show that pitavastatin can suppress oxygen production in endothelial cells by inhibiting Nox. In addition, pitavastatin reduces the expression of eNOS mRNA while increasing the NO dependent response stimulated by acetylcholine and the calcium ionophore,A23187.

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Pitavastatin

(147511-69-1)
HMGA reductase inhibitor

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Perindopril

(82834-16-0)
Labeled Perindopril, intended for use as an internal standard for the quantification of Perindopril by GC- or LC-mass spectrometry.

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Pazopanib

(444731-52-6)
Pazopanib Hydrochloride (GW786034, Votrient, Armala) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM, respectively. Pazopanib is a potent and selective multi-targeted receptor tyrosine kinase inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR-α/β, and c-Kit. Pazopanib is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM,

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Phentolamine

(50-60-2)
Anti-adrenergic.

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Phentolamine methanesulfonate

(65-28-1)
An adrenergic blocking agent.An antihypertensive.Used for the treatment of pheochromocytoma.

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Perindopril erbumine

(107133-36-8)
antibacterial

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Prazosin

(19216-56-9)
Antihypertensive.Prazosin is effective in reducing all grades of hypertension. The drug can be administered alone in mild and (in some instances) moderate hypertension.When the hypertension is moderate or severe, prazosin generally is given in combination with a thiazide diuretic and a -blocker. The antihypertensive actions of prazosin are considerably potentiated by coadministration of thiazides or other types of antihypertensive drugs.
Prazosin may be particularly useful when p

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Pantethine

(16816-67-4)
antilipemic

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Pentoxifylline

(6493-05-6)
A metabolite of Pentifylline. Methylxanthine derivative that improves blood flow by decreasing blood viscosity. Phosphodiesterase inhibitor. Inhibits the synthesis of tumor necrosis factor α (TNF-α).

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Circulatory system drugs are about drugs that have the function of regulating the human circulatory system. The circulatory system is a system of body fluids (including blood, lymph and tissue fluids) and pipes through which circulation flows. Circulatory system drugs mainly include cardiovascular system drugs and diuretics. "Circulatory System Drugs" on ECHEMI covers lipid regulating drugs, angina pectoris drugs, calcium channel blockers, anti-congestive heart failure drugs, antihypertensive drugs, antiarrhythmics drugs, anti shock vasoactive drugs, ace inhibitor, peripheral vasodilators, heart failure treatments and drugs, Anti-atherosclerotic drugs, β-adrenergic receptor blockers and other circulatory system drugs, mainly supply raw materials for such drugs.

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