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Home > Active Pharmaceutical Ingredients > Circulatory System Drugs (Find 15 items)

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Circulatory System Drugs

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Circulatory System Drugs

Sitagliptin

(486460-32-6)
Sitagliptin is a new type of anti-type II diabetes drug approved by the FDA and the first dipeptidyl peptidase-IV inhibitor drug used to treat type II diabetes. Sitagliptin's mechanism of action is different from previous oral hypoglycemic drugs. It improves the ability of diabetic patients' own pancreatic β cells to produce insulin and increases insulin secretion when blood sugar rises, thereby controlling the blood sugar level of diabetic patients. Clinical studies have shown that sitagliptin

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Simvastatin

(79902-63-9)
HMG-CoA reductase inhibitors can reduce the concentration of serum total cholesterol and inhibit cholesterol synthesis. It is used for the treatment of primary hypercholesterolemia with other treatments that are ineffective or intolerable, and the cholesterol level exceeds 7.8mmol/L. Has the effect of lowering cholesterol, low-density lipoprotein cholesterol and very low-density lipoprotein cholesterol

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Sorafenib

(284461-73-0)
A potent RAF kinase inhibitor. Antineoplastic Multiple kinase inhibitor targeting both RAF kinase and receptor tyrosine kinases that promote angiogensis. Antineoplastic. Sorafenib Tosylate (Bay 43-9006, Nexavar) is a small molecular inhibitor of VEGFR, PDGFR, c-Raf and B-Raf with IC50s of 18 nM, 10 nM, 3 nM and 15 nM, respectively. Sorafenib Tosylate (Bay 43-9006) is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM, respectively - See more at: http://www.sel

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Saxagliptin

(361442-04-8)
Saxagliptin is a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing.

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Sumatriptan succinate

(103628-48-4)
Sumatriptan (succinate) is a serotonin 5-hydroxytryptamine 1 (5-HT1) receptor agonist with selective affinity for 5-HT1B and 5-HT1D receptors with IC50 values of 9.3 and 7.3 nM, respectively. It also has affinity for the 5-HT1F receptor (IC50 = 17.8 nM). Sumatriptan (succinate) has been shown to induce vasoconstriction of human middle meningeal arteries (EC50 = 89.9 nM) and reduce vascular inflammation associated with migraines.

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Sparteine

(90-39-1)
It can stimulate the uterus; it can induce labor; it can reduce myocardial stress and conductivity, slow down the heart rate, and suppress the contractility of the heart.

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Sodium ferulate

(24276-84-4)
For the treatment of coronary heart disease, ischemic encephalopathy, leukocytes and thrombocytopenia

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Simendan

(131741-08-7)

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Sodium nitroprusside dihydrate

(13755-38-9)
Reagent for the detection of many organic Compounds, e.g., acetone, aldehydes, also of alkali sulfides, zinc, SO2.

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SARALASIN

(34273-10-4)
Antihypertensive.

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Circulatory system drugs are about drugs that have the function of regulating the human circulatory system. The circulatory system is a system of body fluids (including blood, lymph and tissue fluids) and pipes through which circulation flows. Circulatory system drugs mainly include cardiovascular system drugs and diuretics. "Circulatory System Drugs" on ECHEMI covers lipid regulating drugs, angina pectoris drugs, calcium channel blockers, anti-congestive heart failure drugs, antihypertensive drugs, antiarrhythmics drugs, anti shock vasoactive drugs, ace inhibitor, peripheral vasodilators, heart failure treatments and drugs, Anti-atherosclerotic drugs, β-adrenergic receptor blockers and other circulatory system drugs, mainly supply raw materials for such drugs.

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