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Home > Active Pharmaceutical Ingredients > Circulatory System Drugs (Find 410 items)

Circulatory System Drugs

Dofetilide

(115256-11-6)
Potassium channel blocker

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Dibazole

(621-72-7)
It can relax blood vessels, lower blood pressure, relieve smooth muscle spasm and stimulate the spinal cord. Used for hypertension, angina pectoris, toxemia of pregnancy, gastrointestinal spasm, sequelae of poliomyelitis, peripheral facial paralysis, etc.

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Sparteine

(90-39-1)
It can stimulate the uterus; it can induce labor; it can reduce myocardial stress and conductivity, slow down the heart rate, and suppress the contractility of the heart.

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2,6-Dimethylpiperidine

(504-03-0)
Nanofin is neuropathic blocker, with antihypertensive effect, used for mild to moderate hypertension.

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Nicardipine hydrochloride

(54527-84-3)
Nicardipine is a dihydropyridine L-type calcium channel antagonist that displays antihypertensive and antianginal activity. It is reported to inhibit adenosine A1, A2A, and A3 receptors with Ki values of 19.6, 63.8, and 3.25 μM, respectively, and can inhibit cytochrome P450 3A4 catalytic activity with an IC50 value of 0.148 μM. Additionally, nicardipine has been shown to activate transient receptor potential A1 channels, producing an increase in Ca2+ (EC50 = 0.5 μM).

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Pentaerythritol, tetranitrate

(78-11-5)
Mainly in the manufacture of detonating fuse (Primacord), a waterproof textile filled with powdered PETN.

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Cholestyramine

(11041-12-6)
Lipid-lowering drugs for type Ⅱ hyperlipidemia, atherosclerosis and other diseases. Antihyperlipidemic; ion-exchange resin (bile salts).Cholestyramine resin is the drug of choice for type IIa hyperlipoproteinemia.When used in conjunction with a controlleddiet, it reduces -lipoproteins. The drug is an insolublepolymer and, thus, probably one of the safest because itis not absorbed from the gastrointestinal tract to cause systemictoxic effects.

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Temocapril

(111902-57-9)
Angiotensin-converting enzyme (ACE) inhibitor. Hydrolyzed in vivo to the active diacid metabolite

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Circulatory system drugs are about drugs that have the function of regulating the human circulatory system. The circulatory system is a system of body fluids (including blood, lymph and tissue fluids) and pipes through which circulation flows. Circulatory system drugs mainly include cardiovascular system drugs and diuretics. "Circulatory System Drugs" on ECHEMI covers lipid regulating drugs, angina pectoris drugs, calcium channel blockers, anti-congestive heart failure drugs, antihypertensive drugs, antiarrhythmics drugs, anti shock vasoactive drugs, ace inhibitor, peripheral vasodilators, heart failure treatments and drugs, Anti-atherosclerotic drugs, β-adrenergic receptor blockers and other circulatory system drugs, mainly supply raw materials for such drugs.
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