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Home > Active Pharmaceutical Ingredients > Circulatory System Drugs (Find 410 items)

Circulatory System Drugs

Trandolaprilat

(87679-71-8)
A labeled metabolite of Trandolapril, an antihypertensive.

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Perindoprilat

(95153-31-4)
Perindoprilat is the active metabolite of perindopril, an inhibitor of angiotensin converting enzyme (ACE) that has efficacy against hypertension. Perindoprilat specifically and competitively inhibits ACE in vitro with IC50 values ranging between 1.5 and 3.2 nM. Elimination of perindoprilat is decreased in the elderly and in patients with heart or renal failure.[Cayman Chemical]

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Bepridil

(64706-54-3)
The new calcium antagonists, in order to inhibit the slow channel of calcium ions, selectively expand the coronary arteries, in addition, can inhibit the sodium and potassium ion channels, and thus have the characteristics of class I a, III and IV antiarrhythmic drugs. The half-life is up to 42h. It can be administered once a day. It is well tolerated and has less toxic and side effects. Mainly used for the prevention and treatment of angina pectoris, and can be used for arrhythmia, hypertension

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Cilazapril monohydrate

(92077-78-6)
Angiotensin converting enzyme inhibitor. Used for mild to moderate primary and intractable hypertension.

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(-)-Oxyfedrine

(15687-41-9)
Oxyfedrine acts as a vasodilator affecting the coronary base flow.

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Guanethidine monosulfate

(645-43-2)
It is an adrenal nerve blocker. Its role is to interfere with the release of norepinephrine from the sympathetic nerve endings, and it also depletes the storage of norepinephrine. Therefore, when the adrenal nerve impulses reach the ends, there is no longer enough media to transmit and sympathetic nerve activity Lower blood pressure, lower blood pressure, its antihypertensive effect is strong and lasting. Mainly used for hypertension with moderate and severe diastolic blood pressure, more stubbo

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Circulatory system drugs are about drugs that have the function of regulating the human circulatory system. The circulatory system is a system of body fluids (including blood, lymph and tissue fluids) and pipes through which circulation flows. Circulatory system drugs mainly include cardiovascular system drugs and diuretics. "Circulatory System Drugs" on ECHEMI covers lipid regulating drugs, angina pectoris drugs, calcium channel blockers, anti-congestive heart failure drugs, antihypertensive drugs, antiarrhythmics drugs, anti shock vasoactive drugs, ace inhibitor, peripheral vasodilators, heart failure treatments and drugs, Anti-atherosclerotic drugs, β-adrenergic receptor blockers and other circulatory system drugs, mainly supply raw materials for such drugs.
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