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Circulatory System Drugs

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Fasudil

(103745-39-7)
A potent calcium antagonist vasodilator which is considered to act by employing differentmechanisms from the usual calcium channel blockers since it inhibits (1) calciumionophore A23187 induced contraction in arterial strips and (2) phenylephrine induced contraction in calcium free media suggesting that its site of action is in the intracellularspace. Also reported to potently inhibit Rho-associated Kinase (ROCK IC50= 10.7 uM).

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(+)-Eplerenone

(107724-20-9)
anticancer agent Cardiotonic drugs; antihypertensive drugs, have the characteristics of strong selectivity to aldosterone receptors, good blood pressure lowering effect, and long-lasting effects, and can reverse or reduce many adverse effects of aldosterone on the cardiovascular system.

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Perindopril

(82834-16-0)
Labeled Perindopril, intended for use as an internal standard for the quantification of Perindopril by GC- or LC-mass spectrometry.

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Doxazosin mesylate

(77883-43-3)
Doxazosin ER is indicated for the treatment of the signs and symptoms of benign prostatic hyperplasia

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Felodipine

(72509-76-3)
A dihydropyridine calcium channel blocker

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Circulatory system drugs are about drugs that have the function of regulating the human circulatory system. The circulatory system is a system of body fluids (including blood, lymph and tissue fluids) and pipes through which circulation flows. Circulatory system drugs mainly include cardiovascular system drugs and diuretics. "Circulatory System Drugs" on ECHEMI covers lipid regulating drugs, angina pectoris drugs, calcium channel blockers, anti-congestive heart failure drugs, antihypertensive drugs, antiarrhythmics drugs, anti shock vasoactive drugs, ace inhibitor, peripheral vasodilators, heart failure treatments and drugs, Anti-atherosclerotic drugs, β-adrenergic receptor blockers and other circulatory system drugs, mainly supply raw materials for such drugs.
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