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Home > Natural Products > Coumarin and Derivatives (Find 121 items)

Coumarin and Derivatives

Pimpinellin

(131-12-4)
GABA receptor antagonist, phototoxin Aniselide has an antibacterial effect.

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(+)-Pteryxin

(13161-75-6)
Pteryxin, a coumarin in Peucedanum japonicum Thunb leaves, exerts antiobesity activity[1]. Pteryxin is a potent butyrylcholinesterase (BChE) inhibitor, with an IC50 of 12.96 μg/ml[2].

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(+)-Heraclenol

(31575-93-6)
Angelica dahurica is a brain pungent, warm, enters the lung and stomach meridian. Dispel wind, dry dampness, relieve pain, drain pus, grow muscles. ① Treat colds, colds, headaches, nasal congestion, toothache, brow bone pain, nasal cavity, intestinal wind and hemorrhoids, red vaginal discharge. ② Treat carbuncle and sore, decoction and study the powder to adjust the application; skin itching, snake bite. Research and adjust the application. Angelica dahurica leaves: Decoction and washing to cure

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8-Geranyloxypsoralen

(7437-55-0)
8-Geranyloxypsoralen is a furanocoumarin isolated from grapefruit, acts as a potent inhibitor of P450 3A4 (CYP3A4) with an IC50 of 3.93 μM[1].

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Auraptene

(495-02-3)
Auraptene is a natural bioactive monoterpene coumarin ether. Auraptene has shown a remarkable effect in the prevention of degenerative diseases. Orange peel oil lactone has anti-inflammatory, relieving cough and reducing phlegm.

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Skimmin

(93-39-0)
Incoside has kidney protection and anti-inflammatory effects.

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Nodakenetin

(495-32-9)
Nodakenetin, isolated from Angelica decursiva, possesses antioxidant anti-inflammatory activities. Nodakenetin has the potential to be an antiarthritic and nerve tonic[1][2].

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3,4-Dihydro-8-hydroxy-3-(4-hydroxyphenyl)-1H-2-benzopyran-1-one

(480-47-7)
ChEBI: A member of the class of dihydroisocoumarins that is 3,4-dihydroisocoumarin substituted by a hydroxy group at position 8 and a 4-hydroxyphenyl group at position 3. It has been isolated from the roots of Scorzonera judaica and exhibits anti-all rgic activity.

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(+)-Heraclenin

(2880-49-1)
Heraclenin, a natural furanocoumarin, isolated from the root parts of the plant Prangos pabularia. Heraclenin significantly inhibits T cell receptor-mediated proliferation in human primary T cells in a concentration-dependent manner by targeting nuclear factor of activated T-cells (NFAT)[1].

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Coumarin, found naturally in black cougar, whiff chrysanthemum, wild viburnum, and orchid, has fresh hay and coumarin flavors, and is generally not eaten, and is allowed for tobacco and external use. Mainly divided into: simple, furan, pyran, double coumarin, isocoumarin and other coumarin.
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