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Home > Active Pharmaceutical Ingredients > Digestive System Drugs (Find 2 items)

Vonoprazan

(881681-00-1)
TAK-438 (free base) is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+ ATPase with IC50 of 19 nM (pH 6.5), controls gastric acid secretion.IC50 value: 19 nM [1]Target: H+/K+ ATPasein vitro: TAK-438 is a pyrrole derivative with a chemical structure that is completely different from the P-CABs developed to date. TAK-438 inhibits gastric H+/K+ ATPase activity in a concentration-dependent manner. Under neutral conditions (pH 7.5), the inhibitory activity of

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Digestive system drugs are currently one of the most commonly used drugs in clinic. Digestive System Drugs mainly include liver disease drugs, antacid and mucosal protective drugs, cholagogue drugs, appetite suppressants and other diet pills, gastrointestinal motility drugs, gastrointestinal antispasmodic drugs, laxatives and antidiarrheal Medicines, gastric acid Inhibitors, emetics and antiemetics, digestant drugs and other digestive system drugs. The "Digestive System Drugs" of ECHEMI classification list mainly supplies APIs for such drugs.
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