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Drugs Influencing Immune Function

Anti-CD3

(140608-64-6)
Monoclonal antibody (immunosuppressant).Muromonab-(CD3) alters the cell-mediated immune response by binding to the CD3 (cluster of differentiation antigen, T3) glycoprotein on T lymphocytes. It is used for the prevention of acute allograft rejection in kidney and hepatic transplants and as prophylaxis in cardiac transplantation. It is also used to deplete T cells in marrow from donors before bone marrow transplantation.

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There are two types of drugs that affect immune function: immunosuppressive drugs can suppress the immune response of those with excessive immune activity; immune-enhancing drugs can support the immune function of those with low immune function. There are five types of commonly used immunosuppressants: glucocorticoids, microbial metabolites, antimetabolites, polyclonal and monoclonal anti-lymphocyte antibodies, and alkylating agents. At present, commonly used immune-enhancing drugs are chemical synthetic drugs levamisole, isoprinosine, etc., human or animal immune products thymosin, transfer factor, interferon, interleukin, etc., BCG vaccines derived from microorganisms and other sources of biological polysaccharides, active ingredients of traditional Chinese medicine Wait. "Drugs Influencing Immune Function" on ECHEMI mainly supplies APIs for drugs that affect immune function.

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