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Immune System Drugs APIs
Drugs Influencing Immune Function
Everolimus
(159351-69-6)
Everolimus is a semi-synthetic macrocyclic lactone prepared from rapamycin by selective alkylation of the 42-hydroxy group with a silyl-protected hydroxyethyl triflate moiety, followed by addition of an ethylhydroxy moiety to provide greater stability and bioavailability. Like all tacrolimus analogues, everolimus binds to receptor protein, FKBP12. The complex then binds to mTOR preventing it from interacting with target proteins. Everolimus is extensively cited in the literature with over 2,000
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There are two types of drugs that affect immune function: immunosuppressive drugs can suppress the immune response of those with excessive immune activity; immune-enhancing drugs can support the immune function of those with low immune function. There are five types of commonly used immunosuppressants: glucocorticoids, microbial metabolites, antimetabolites, polyclonal and monoclonal anti-lymphocyte antibodies, and alkylating agents. At present, commonly used immune-enhancing drugs are chemical synthetic drugs levamisole, isoprinosine, etc., human or animal immune products thymosin, transfer factor, interferon, interleukin, etc., BCG vaccines derived from microorganisms and other sources of biological polysaccharides, active ingredients of traditional Chinese medicine Wait. "Drugs Influencing Immune Function" on ECHEMI mainly supplies APIs for drugs that affect immune function.
