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Immune System Drugs APIs
Drugs Influencing Immune Function
Rapamycin
(53123-88-9)
Rapamycin is an immunosuppressant that is used primarily to prevent the rejection of organ and bone marrow transplant. It was first described as a potent inhibitor of IL-2 activation of lymphocytes (IC50 = 5 pM). It is now known that rapamycin specifically interacts with the cytosolic FK-binding protein 12 (FKBP12) to form a complex which inhibits the mammalian target of rapamycin (mTOR) pathway by directly binding to mTOR Complex 1 (mTORC1). Rapamycin and other inhibitors of mTORC1 signaling sh
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RAT IL-2
(95568-40-4)
It is used to treat AIDS and tumors, and has a certain effect on viral, bacterial, fungal or protozoan infections such as hepatitis, tuberculosis, and nodular leprosy. Adverse reactions and contraindications: fever, nausea, vomiting, fatigue and discomfort can be seen with systemic medication. Occasionally face redness, chills, diarrhea, edema and symptomatic hypertension.
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There are two types of drugs that affect immune function: immunosuppressive drugs can suppress the immune response of those with excessive immune activity; immune-enhancing drugs can support the immune function of those with low immune function. There are five types of commonly used immunosuppressants: glucocorticoids, microbial metabolites, antimetabolites, polyclonal and monoclonal anti-lymphocyte antibodies, and alkylating agents. At present, commonly used immune-enhancing drugs are chemical synthetic drugs levamisole, isoprinosine, etc., human or animal immune products thymosin, transfer factor, interferon, interleukin, etc., BCG vaccines derived from microorganisms and other sources of biological polysaccharides, active ingredients of traditional Chinese medicine Wait. "Drugs Influencing Immune Function" on ECHEMI mainly supplies APIs for drugs that affect immune function.
