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Home > Biochemical Engineering > Inflammation Mediators (Find 32 items)

Inflammation Mediators

11-deoxy-15-keto-13,14-dihydro-11 beta,16-cycloprostaglandin E2

(74158-09-1)
Bicyclo prostaglandin E2 (bicyclo PGE2) is a stable breakdown product of PGE2 and 13,14-dihydro-15-keto PGE2 . Bicyclo PGE2 is a stable, base-catalyzed transformation product of 13,14-dihydro-15-keto PGE2. 13,14-dihydro-15-keto PGE2 itself is a metabolite of PGE2 found in human plasma at a median level of 20-25 pg/ml. Due to the inherent instability of 13,14-dihydro-15-keto PGE2, it is advisable to quantify it as bicyclo PGE2 to estimate PGE2 biosynthesis or metabolism in vivo.

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13,14-Dihydro-15-keto-PGE1

(5094-14-4)

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15-hydroxyeicosatrienoicacid

(82451-61-4)

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Inflammatory mediators refer to chemically active substances that are produced and released by local tissues or plasma under the action of inflammatory factors, and participate in or cause inflammatory reactions, so they are also called chemical mediators. There are two types, exogenous (bacteria and their products) and endogenous, but mainly the latter. Endogenous can be divided into two categories: cell-derived and plasma-derived. "Cell-derived" include vasoactive amines, prostaglandins, leukotrienes, lysosomal components and lymphokines, etc. The inflammatory mediators produced by plasma include kinin system, complement system, coagulation system and fibrinolytic system.
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