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Home > Biochemical Engineering > Inflammation Mediators (Find 5 items)

Inflammation Mediators

TXB2

(54397-85-2)
TXB2 is a stable, biologically inert metabolite formed from the non-enzymatic hydrolysis of TXA2, which has a half-life of about 30 seconds. Urinary analysis of TXB2 accurately reflects intrarenal TXA2 synthesis, while measurement of 11-dehydro and 2,3-dinor thromboxane metabolites gives the best estimate of systemic TXA2 secretion.

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Thromboxane B3

(71953-80-5)
Thromboxane B3 (TXB3) is the stable hydrolysis product of TXA3 synthesized fromeicosapentaenoic acid (EPA; ) by COX and thromboxane synthase. It is biosynthesized in various tissues such as seminal vesicles, lung, PMNL, and ocular tissues.[Cayman Chemical]

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TFC612

(83058-69-9)

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Inflammatory mediators refer to chemically active substances that are produced and released by local tissues or plasma under the action of inflammatory factors, and participate in or cause inflammatory reactions, so they are also called chemical mediators. There are two types, exogenous (bacteria and their products) and endogenous, but mainly the latter. Endogenous can be divided into two categories: cell-derived and plasma-derived. "Cell-derived" include vasoactive amines, prostaglandins, leukotrienes, lysosomal components and lymphokines, etc. The inflammatory mediators produced by plasma include kinin system, complement system, coagulation system and fibrinolytic system.
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