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Home > Biochemical Engineering > Inflammation Mediators (Find 128 items)

Inflammation Mediators

D-cloprostenol

(54276-21-0)
(+)-Cloprostenol is a prostaglandin F2α (PGF2α) analogue, and shows selective agonistic activity at the prostaglandin receptor.

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Beraprost

(88430-50-6)
Platelet aggregation inhibitor; stable analog of Prostacyclin. Antithrombotic; vasodilator (peripheral).

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Latanoprostene bunod

(860005-21-6)

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ETYA

(1191-85-1)
Eicosatetraynoic acid (ETYA) is a nonspecific inhibitor of cyclooxygenase and lipoxygenase (ID50=8 μM and 4 μM, respectively)[1]. Eicosatetraynoic acid (ETYA) activates PPARα and PPARγ chimeras at 10 µM[2].

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Leukotriene B4

(71160-24-2)

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2-Arachidonylglycerol

(53847-30-6)
2-Arachidonoylglycerol is a major endocannabinoid, which can inhibit synaptic transmission by presynaptic cannabinoid CB1 receptors. It plays an inhibitory role in the bombesin-induced activation of central adrenomedullary outflow in rats.

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11-Dehydro-TXB2

(67910-12-7)
A metabolite of Thromboxane that is an in vivo markers of oxidative stress and platelet activation. It is associated with adverse cardiovascular events in Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT).

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Inflammatory mediators refer to chemically active substances that are produced and released by local tissues or plasma under the action of inflammatory factors, and participate in or cause inflammatory reactions, so they are also called chemical mediators. There are two types, exogenous (bacteria and their products) and endogenous, but mainly the latter. Endogenous can be divided into two categories: cell-derived and plasma-derived. "Cell-derived" include vasoactive amines, prostaglandins, leukotrienes, lysosomal components and lymphokines, etc. The inflammatory mediators produced by plasma include kinin system, complement system, coagulation system and fibrinolytic system.
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