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Inhibitors

1H-Indole-3-ethanamine, N,N-dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-, benzoate (1:1)

(145202-66-0)

A selective serotonin 5-HTID receptor agonist.Structurally derived from tryptamine

1H-Indole-3-ethanamine, N,N-dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-, benzoate (1:1) SDS

- / 99.00%

LEAP CHEM CO., LTD.
Pharmacy Grade / 99%

XI'AN ZHONGSHI BIOENGR CO.,LTD.
Pharmaceutical Grade / 99%

$100/KG EXW

Shandong Airuike Chemical Co., Ltd.
- / 99%

Hanzhong Han Traceability Biological Tec

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1H-Imidazole, 5-[1-(2,3-dimethylphenyl)ethyl]-, hydrochloride (1:1)

(86347-15-1)

α2-Adrenergic agonist. Sedative; analgesic.

1H-Imidazole, 5-[1-(2,3-dimethylphenyl)ethyl]-, hydrochloride (1:1) SDS

- / 99.00%

LEAP CHEM CO., LTD.
Pharmacy Grade / 99%

$7-8/G FOB

XI'AN HORLDEN BIO INDUSTRIES INC
Pharmacy Grade / 99%

$20-25/KG FOB

Shaanxi TNJONE Pharmaceutical Co., Ltd
Hangzhou Dawn Ray Pharmaceutical Co.,Ltd

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1H-Indole-5-ethanesulfonamide, N-methyl-3-(1-methyl-4-piperidinyl)-, hydrochloride (1:1)

(143388-64-1)

laxative

1H-Indole-5-ethanesulfonamide, N-methyl-3-(1-methyl-4-piperidinyl)-, hydrochloride (1:1) SDS

- / 99.00%

LEAP CHEM CO., LTD.
Industrial Grade / 99%

henan kanbei chemical co.,ltd
Industrial Grade / 99.0%

Shaanxi Dideu Medichem Co. Ltd
Dayang Chem (Hangzhou) Co.,Ltd

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1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]cyclopropanecarboxamide

(1152311-62-0)

VX-661 is a second F508del CFTR corrector and help CFTR protein reach the cell surface.

1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]cyclopropanecarboxamide SDS

- / 99.00%

LEAP CHEM CO., LTD.
Industrial Grade / 99%

henan kanbei chemical co.,ltd
Pharmacy Grade / 98.5%

$0.1-1000/KG FOB

wuhan RLD Bio-Medical
Industrial Grade / 99%

Shaanxi Dideu Medichem Co. Ltd

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1H-Pyrazole-3-acetamide, 5-[[7-[3-[ethyl(2-hydroxyethyl)amino]propoxy]-4-quinazolinyl]amino]-N-(3-fluorophenyl)-

(722544-51-6)

AZD1152-HQPA is a a highly selective inhibitor of aurora-B kinase. AZD1152-HQPA has been shown to inhibit osteosarcoma cell line U2-OS cells proliferation. AZD1152-HQPA was also shown to be an effective apoptosis-inducing agent in acute myeloid leukemia cell lines and primary acute myeloid leukemia cultures.

1H-Pyrazole-3-acetamide, 5-[[7-[3-[ethyl(2-hydroxyethyl)amino]propoxy]-4-quinazolinyl]amino]-N-(3-fluorophenyl)- SDS

- / 99.00%

LEAP CHEM CO., LTD.
Creative Enzymes
Industrial Grade / 99%

Shaanxi Dideu Medichem Co. Ltd
Dayang Chem (Hangzhou) Co.,Ltd

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1-Azetidinecarbothioic acid 2-[1-(2-pyridinyl)ethylidene]hydrazide

(71555-25-4)

NSC319726 is a mutant p53R175 reactivator; inhibits growth of fibroblasts expressing the p53R175 mutation (IC50 = 8 nM); shows no inhibition for p53 wild-type cells.IC50 value: 8 nM [1]Target: mutant p53R175 reactivatorin vitro: For NSC319726, the effect was even greater as the IC50for the 175 mutant was 8 nM while the IC50 of the WT was not reached. NSC319726 did not induce WT p53 protein levels or transcriptional activity as common cytotoxic agents such as etoposide do in vitro. NSC319

1-Azetidinecarbothioic acid 2-[1-(2-pyridinyl)ethylidene]hydrazide SDS

- / 99.00%

LEAP CHEM CO., LTD.
Creative Enzymes
Dayang Chem (Hangzhou) Co.,Ltd
Industrial Grade / 99%

Shaanxi Dideu Medichem Co. Ltd

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1-[4-[4-(1-Oxopropyl)-1-piperazinyl]-3-(trifluoromethyl)phenyl]-9-(3-quinolinyl)benzo[h]-1,6-naphthyridin-2(1H)-one

(1222998-36-8)

Torin 1 is a potent and selective mTOR inhibitor (IC50 = 2 - 10 nM for mTORC1 and mTORC2). Displays 200-fold selectivity for mTOR over DNA-PK, ATM and hVps34.

1-[4-[4-(1-Oxopropyl)-1-piperazinyl]-3-(trifluoromethyl)phenyl]-9-(3-quinolinyl)benzo[h]-1,6-naphthyridin-2(1H)-one SDS

- / 99.00%

LEAP CHEM CO., LTD.
Creative Enzymes
Industrial Grade / 99%

Shaanxi Dideu Medichem Co. Ltd
Industrial Grade / 99%

CHEMLYTE SOLUTIONS CO.,LTD

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1-(3-(Trifluoromethyl)-4-(piperazin-1-yl)phenyl)-8-(6-methoxypyridin-3-yl)-3-methyl-1H-imidazo[4,5-c]quinolin-2(3H)-one maleic acid salt

(1245537-68-1)

NVP-BGT226 is a potent pan-class I PI3K and mTOR catalytic inhibitor with IC50s of 4 nM, 63 nM and 38 nM for PI3Kα, PI3Kβ and PI3Kγ.

1-(3-(Trifluoromethyl)-4-(piperazin-1-yl)phenyl)-8-(6-methoxypyridin-3-yl)-3-methyl-1H-imidazo[4,5-c]quinolin-2(3H)-one maleic acid salt SDS

- / 99%

Creative Enzymes
Industrial Grade / 99%

Shaanxi Dideu Medichem Co. Ltd
Dayang Chem (Hangzhou) Co.,Ltd
LEAP CHEM CO., LTD.

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17-DMAG

(467214-21-7)

Treatment of solid and hematological tumors.

17-DMAG SDS

Industrial grade / 98%

Shaanxi Cuikang Pharmaceutical Technolog
Industrial Grade / 99%

henan kanbei chemical co.,ltd
- / 95%

Creative Enzymes
Shaanxi Dideu Medichem Co. Ltd

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1,1′-[1,4-Phenylenebis(methylene)]bis[1,4,8,11-tetraazacyclotetradecane] hydrochloride (1:8)

(155148-31-5)

A specific CXCR4 antagonist.

1,1′-[1,4-Phenylenebis(methylene)]bis[1,4,8,11-tetraazacyclotetradecane] hydrochloride (1:8) SDS

- / 99.00%

LEAP CHEM CO., LTD.
Industrial Grade / 99%

Shaanxi Dideu Medichem Co. Ltd
Dayang Chem (Hangzhou) Co.,Ltd
Industrial Grade / 99%

CHEMLYTE SOLUTIONS CO.,LTD

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Small molecule inhibitors are a type of molecules that can interact with proteins and reduce the biological activity of target proteins, including enzyme inhibitors, transcription factor inhibitors, and ion channel blockers. It acts on popular signaling pathways, popular targets and popular research fields: MAPK, PI3K, JAK / STAT and other signaling pathways, HDAC, Aurora kinase, CDK and cell cycle regulators, integrase / protease, etc. Research fields such as epigenetics, CNS, GPCR, anti-virus, antibacterial / anti-inflammatory. It is an effective tool for cell biology research.

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Inhibitors

1H-Indole-3-ethanamine, N,N-dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-, benzoate (1:1)

1H-Imidazole, 5-[1-(2,3-dimethylphenyl)ethyl]-, hydrochloride (1:1)

1H-Indole-5-ethanesulfonamide, N-methyl-3-(1-methyl-4-piperidinyl)-, hydrochloride (1:1)

1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]cyclopropanecarboxamide

1H-Pyrazole-3-acetamide, 5-[[7-[3-[ethyl(2-hydroxyethyl)amino]propoxy]-4-quinazolinyl]amino]-N-(3-fluorophenyl)-

Source Inhibitors Products Supply

1-Azetidinecarbothioic acid 2-[1-(2-pyridinyl)ethylidene]hydrazide

1-[4-[4-(1-Oxopropyl)-1-piperazinyl]-3-(trifluoromethyl)phenyl]-9-(3-quinolinyl)benzo[h]-1,6-naphthyridin-2(1H)-one

1-(3-(Trifluoromethyl)-4-(piperazin-1-yl)phenyl)-8-(6-methoxypyridin-3-yl)-3-methyl-1H-imidazo[4,5-c]quinolin-2(3H)-one maleic acid salt

17-DMAG

1,1′-[1,4-Phenylenebis(methylene)]bis[1,4,8,11-tetraazacyclotetradecane] hydrochloride (1:8)

Source Inhibitors Raw Materials by Region

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