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Home > Biochemical Engineering > Inhibitors (Find 73 items)

Inhibitors

Apixaban

(503612-47-3)
Apixaban, sold under the tradename Eliquis, is an anticoagulant for the treatment of venous thromboembolic events. It is taken by mouth. It is a direct factor Xa inhibitor.Apixaban was approved in Europe in 2012. It was approved in the U.S. in 2014 for treatment and secondary prophylaxis of deep vein thrombosis (DVT) and pulmonary embolism (PE). It is being developed in a joint venture by Pfizer and Bristol-Myers Squibb.

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Abiraterone

(154229-19-3)
Abiraterone, a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.

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Alogliptin

(850649-61-5)
Alogliptin is an oral antihyperglycemic agent that is a selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4).Antidiabetic agent.

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Azathioprine

(446-86-6)
An immunosuppressive antimetabolite.Also active as disease modifying antirheumatic drug (DMARD). Azathioprine is a purine analog with immunosuppressive effects.

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Atomoxetine

(83015-26-3)
A compound active at novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases.

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Apremilast

(608141-41-9)
Apremilast , an oral phosphodiesterase 4 inhibitor is used in the treatment of psoriatic arthritis.

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Ambrisentan

(177036-94-1)
Nonpeptide endothelin ETA receptor antagonist. Antihypertensive

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Small molecule inhibitors are a type of molecules that can interact with proteins and reduce the biological activity of target proteins, including enzyme inhibitors, transcription factor inhibitors, and ion channel blockers. It acts on popular signaling pathways, popular targets and popular research fields: MAPK, PI3K, JAK / STAT and other signaling pathways, HDAC, Aurora kinase, CDK and cell cycle regulators, integrase / protease, etc. Research fields such as epigenetics, CNS, GPCR, anti-virus, antibacterial / anti-inflammatory. It is an effective tool for cell biology research.

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