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Home > Biochemical Engineering > Inhibitors (Find 41 items)

Biochemical Engineering

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Inhibitors

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Inhibitors

Darapladib

(356057-34-6)
Treatment of atherosclerosis.

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DBeQ

(177355-84-9)
The ATPase p97 is an ubiquitin-selective chaperone known to play a critical role in the degradation of misfolded membrane and secretory proteins and has been linked to various cellular processes that require unfolding and disassembly of protein complexes. DBeQ is a selective, reversible, and ATP-competitive inhibitor of the ATPase p97 (Ki = 3.2 μM; IC50 = 1.5 μM). It does not exhibit activity when tested against a panel 170 protein kinases at concentrations as high as 15 μM. At 10 μM it blocks e

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Diphemanil methyl sulfate

(62-97-5)
Bronchodilatator;Anticholinergic

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Dizocilpine

(77086-21-6)
Neuroprotective.

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DCC-2618

(1225278-16-9)

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Droxinostat

(99873-43-5)
Droxinostat is a histone deacetylase selective inhibitor and is used in cancer therapy and cancer research. Droxinostat is a selective inhibitor of HDAC3, HDAC6, and HDAC8.

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Debio-1347

(1265229-25-1)

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Dovitinib Dilactic acid (TKI258 Dilactic acid)

(852433-84-2)
Dovitinib (TKI258, CHIR-258) is a multitargeted tyrosine kinase inhibitor of FLT3 and c-KIT with IC50 of 1 nM and 2 nM, respectively.

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Davunetide

(211439-12-2)

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Degrasyn

(856243-80-6)
Degrasyn (WP1130) is a cell-permeable deubiquitinase (DUB) inhibitor, directly inhibiting DUB activity of USP9x, USP5, USP14, and UCH37. Degrasyn has been shown to downregulate the antiapoptotic proteins Bcr-Abl and JAK2.

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Small molecule inhibitors are a type of molecules that can interact with proteins and reduce the biological activity of target proteins, including enzyme inhibitors, transcription factor inhibitors, and ion channel blockers. It acts on popular signaling pathways, popular targets and popular research fields: MAPK, PI3K, JAK / STAT and other signaling pathways, HDAC, Aurora kinase, CDK and cell cycle regulators, integrase / protease, etc. Research fields such as epigenetics, CNS, GPCR, anti-virus, antibacterial / anti-inflammatory. It is an effective tool for cell biology research.

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South Korea

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