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Home > Biochemical Engineering > Inhibitors (Find 21 items)

Inhibitors

Enzalutamide

(915087-33-1)
Enzalutamide (MDV3100) is an androgen-receptor (AR) antagonist with IC50 of 36 nM

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Etravirine

(269055-15-4)
Etravirine (TMC125) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV.

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Eletriptan hydrobromide

(177834-92-3)
A second generation triptan drug used in the treatment of migraine headaches.

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Entinostat

(209783-80-2)
Entinostat is an emerging HDACi (histone deacetylase inhibitor). Entinostat is used for treatment of solid tumors and hematologic malignancies.

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Elvitegravir

(697761-98-1)
Elvitegravir is a quinolone antibiotic that inhibits the integrase of HIV-1 (IC50 = 7.2 nM). It blocks the integration of HIV-1 cDNA through the inhibition of DNA strand transfer. Elvitegravir is used in combination with a pharmacoenhancer and nucleoside/nucleotide reverse transcriptase inhibitors to block HIV-1 replication in vivo.[Cayman Chemical]

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Enzastaurin

(170364-57-5)
PKCβ-selective inhibitor, suppresses angiogenesis.

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Elacridar

(143664-11-3)
A prototypical BCRP inhibitor. Inhibits the Bcrp1-mediated transport.

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Evacetrapib

(1186486-62-3)
Evacetrapib is a potent and selective of CETP inhibitor, which inhibits human recombinant CETP protein (IC50 5.5 nM) and CETP activity in human plasma (IC50 36 nM) in vitro.

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Small molecule inhibitors are a type of molecules that can interact with proteins and reduce the biological activity of target proteins, including enzyme inhibitors, transcription factor inhibitors, and ion channel blockers. It acts on popular signaling pathways, popular targets and popular research fields: MAPK, PI3K, JAK / STAT and other signaling pathways, HDAC, Aurora kinase, CDK and cell cycle regulators, integrase / protease, etc. Research fields such as epigenetics, CNS, GPCR, anti-virus, antibacterial / anti-inflammatory. It is an effective tool for cell biology research.

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