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Home > Biochemical Engineering > Inhibitors (Find 1083 items)

Inhibitors

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2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one

(154447-36-6)
LY294002 is a selective phosphatidylinositol 3-kinase (PI3K) inhibitor with a 2.7-fold greater potency than quercetin. LY294002 inhibits purified PI3K with an IC50 of 1.4 μM.

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Dabrafenib

(1195765-45-7)
Dabrafenib is an ATP-competitive inhibitor of Raf with IC50s of 5 nM and 0.6 nM for C-Raf and B-RafV600E, respectively.

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Panobinostat

(404950-80-7)
The novel histone deacetylase inhibitor, LBH589, induces expression of DNA damage response genes and apoptosis in Ph- acute lymphoblastic leukemia cells.

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Detomidine hydrochloride

(90038-01-0)
Detomidine produce dose-dependent sedative and analgesic effects, mediatated by activation of α2 catecholamine receptors.

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Apalutamide

(956104-40-8)
Apalutamide (ARN-509) is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM.

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Ribociclib

(1211441-98-3)
Ribociclib (LEE011) is a highly specific CDK4/6 inhibitor with IC50s of 10 nM and 39 nM, respectively.

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Masitinib

(790299-79-5)
Masitinib controlled-release implant for treating solid neoplasm.

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Small molecule inhibitors are a type of molecules that can interact with proteins and reduce the biological activity of target proteins, including enzyme inhibitors, transcription factor inhibitors, and ion channel blockers. It acts on popular signaling pathways, popular targets and popular research fields: MAPK, PI3K, JAK / STAT and other signaling pathways, HDAC, Aurora kinase, CDK and cell cycle regulators, integrase / protease, etc. Research fields such as epigenetics, CNS, GPCR, anti-virus, antibacterial / anti-inflammatory. It is an effective tool for cell biology research.

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