 Home > Biochemical Engineering > Inhibitors (Find 1083 items)

Biochemical Engineering

Inhibitors

17-DMAG

(467214-21-7)

Treatment of solid and hematological tumors.

17-DMAG SDS

Industrial grade / 98%

Shaanxi Cuikang Pharmaceutical Technolog
Industrial Grade / 99%

henan kanbei chemical co.,ltd
- / 95%

Creative Enzymes
Shaanxi Dideu Medichem Co. Ltd

Request for quotation , get quotes from more suppliers.

5,5′-(2,5-Furandiyl)bis[2-thiophenemethanol]

(213261-59-7)

NSC 652287, a DNA damaging agent. It induces p53 tumor suppressor protein.

5,5′-(2,5-Furandiyl)bis[2-thiophenemethanol] SDS

Creative Enzymes
Industrial Grade, Feed Grade, Food Grade, Pharma Grade / 99%

$11.11/KG EXW

Shaanxi Dideu Medichem Co. Ltd
Dayang Chem (Hangzhou) Co.,Ltd
LEAP CHEM CO., LTD.

Request for quotation , get quotes from more suppliers.

Zotarolimus

(221877-54-9)

A tetrazole-containing Rapamycin analog as immunomodulator and useful in the treatment of restenosis and immune and autoimmune diseases.

Zotarolimus SDS

- / 99.00%

LEAP CHEM CO., LTD.
Industrial Grade, Feed Grade, Food Grade, Pharma Grade / 99%

$11.11/KG EXW

Shaanxi Dideu Medichem Co. Ltd
Industrial Grade / 99%

CHEMLYTE SOLUTIONS CO.,LTD
HANGZHOU JHECHEM CO LTD

Request for quotation , get quotes from more suppliers.

Ispinesib

(336113-53-2)

The kinesin-like spindle protein Eg5 (also known as kinesin-5, kinesin family protein 11, or Kif11) is a motor protein that is essential for establishing a bipolar spindle during mitosis both in normal and tumor cells. Ispinesib is a cell-permeable, allosteric inhibitor of Eg5 (Ki app = 2.3 nM) with >10,000-fold selectivity for Eg5 over a range of other mitotic kinesins. It induces a monopolar spindle phenotype, leading to the activation of a spindle assembly checkpoint, mitotic arrest, and subs

Ispinesib SDS

- / 99.00%

LEAP CHEM CO., LTD.
Industrial Grade / 99.00%

Shaanxi Dideu Medichem Co. Ltd
Dayang Chem (Hangzhou) Co.,Ltd
Industrial Grade / 99%

CHEMLYTE SOLUTIONS CO.,LTD

Request for quotation , get quotes from more suppliers.

2-(Difluoromethyl)-1-(4,6-di-4-morpholinyl-1,3,5-triazin-2-yl)-1H-benzimidazole

(475110-96-4)

ZSTK474 is a triazine derivative that acts as an inhibitor of class I phosphatidylinositol 3-kinase (PI3K) isoforms (IC50s = 17, 53, and 6 nM for p110β, -γ, and -δ, respectively). It is selective for PI3K, as it has negligible activity against 139 other kinases when tested at 30 μM. ZSTK474 is orally bioavailable and shows strong antitumor activity against human cancer xenografts in mice. The efficacy of ZSTK474 against certain cancer cells and tumors can be enhanced by combination therapy.

2-(Difluoromethyl)-1-(4,6-di-4-morpholinyl-1,3,5-triazin-2-yl)-1H-benzimidazole SDS

- / 99.00%

LEAP CHEM CO., LTD.
Dayang Chem (Hangzhou) Co.,Ltd
Industrial Grade / 99%

CHEMLYTE SOLUTIONS CO.,LTD
- / 0.98%

SUZHOU ARTK MEDCHEM CO.,LTD.

Request for quotation , get quotes from more suppliers.

A66

(1166227-08-2)

This potent and highly selective p110α inhibitor (FW = 393.53; CAS 1166227-08-2; Solubility: 79 mg/mL DMSO, 1 mg/mL H2O), also known as (2S)-N1-(5-(2-tert-butylthiazol-4-yl)-4-methylthiazol-2-yl)pyrrolidine-1, 2-dicarboxamide, has a IC50 value of 32 nM for the wild-type phosphoinositide-3 kinase p110 α as well as oncogenic forms of p110α such as p110α E545K (IC50 = 43 nM) and p110α H1047R (IC50 = 43 nM). A66 inhibition also demonstrated that cancer-specific mutations in the iSH2 (inter-SH2) and

A66 SDS

- / 99%

Creative Enzymes
Industrial Grade / 99%

Shaanxi Dideu Medichem Co. Ltd
LEAP CHEM CO., LTD.
Industrial Grade / 99%

CHEMLYTE SOLUTIONS CO.,LTD

Request for quotation , get quotes from more suppliers.

Crenolanib

(670220-88-9)

Crenolanib is an orally bioavailable, selective inhibitor of type III tyrosine kinases with nanomolar potencies against platelet-derived growth factor receptor α (PDGFRα) and PDGFRβ and Fms-related tyrosine kinase 3 (FLT3; IC50s = 11, 3.2, and 4 nM, respectively). It also inhibits medically-relevant mutant forms of these kinases, including the D842V-containing form of PDGFR and D835Y and internal tandem duplication mutations of FLT3, at nanomolar concentrations. Crenolanib is more than 100-fold

Crenolanib SDS

- / 99%

Creative Enzymes
Industrial Grade / 99%

Shaanxi Dideu Medichem Co. Ltd
LEAP CHEM CO., LTD.
Industrial Grade / 99%

CHEMLYTE SOLUTIONS CO.,LTD

Request for quotation , get quotes from more suppliers.

N-[4-[[6-Methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenyl]benzamide

(331771-20-1)

It is a potent and selective inhibitor of Aurora B kinase. Cells treated with ZM-447439 progress through interphase, enter mitosis and assemble bipolar spindles but chromosome alignment, segregation and cytokinesis all fail. It induces apoptosos in Hep2 cancer cells and in acute myeloid leukemia cell lines but its propensity to induce polyploidy does not inevitably result in apoptosis.

N-[4-[[6-Methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenyl]benzamide SDS

Creative Enzymes
Industrial Grade / 99.00%

Shaanxi Dideu Medichem Co. Ltd
Industrial Grade / 99%

CHEMLYTE SOLUTIONS CO.,LTD
Conier Chem&Pharma Limited

Request for quotation , get quotes from more suppliers.

1,1′-[1,4-Phenylenebis(methylene)]bis[1,4,8,11-tetraazacyclotetradecane] hydrochloride (1:8)

(155148-31-5)

A specific CXCR4 antagonist.

1,1′-[1,4-Phenylenebis(methylene)]bis[1,4,8,11-tetraazacyclotetradecane] hydrochloride (1:8) SDS

- / 99.00%

LEAP CHEM CO., LTD.
Industrial Grade / 99%

Shaanxi Dideu Medichem Co. Ltd
Dayang Chem (Hangzhou) Co.,Ltd
Industrial Grade / 99%

CHEMLYTE SOLUTIONS CO.,LTD

Request for quotation , get quotes from more suppliers.

N-[4-[1-(1,4-Dioxaspiro[4.5]dec-8-yl)-4-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl]phenyl]-N'-methylurea

(1144068-46-1)

WYE-125132 is a highly potent, ATP-competitive and specific mammalian target of rapamycin (mTOR) inhibitor.

N-[4-[1-(1,4-Dioxaspiro[4.5]dec-8-yl)-4-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl]phenyl]-N'-methylurea SDS

Industrial Grade / 99%

henan kanbei chemical co.,ltd
- / 99%

Creative Enzymes
Industrial Grade / 99%

Shaanxi Dideu Medichem Co. Ltd
Dayang Chem (Hangzhou) Co.,Ltd

Request for quotation , get quotes from more suppliers.

Go to Page

Small molecule inhibitors are a type of molecules that can interact with proteins and reduce the biological activity of target proteins, including enzyme inhibitors, transcription factor inhibitors, and ion channel blockers. It acts on popular signaling pathways, popular targets and popular research fields: MAPK, PI3K, JAK / STAT and other signaling pathways, HDAC, Aurora kinase, CDK and cell cycle regulators, integrase / protease, etc. Research fields such as epigenetics, CNS, GPCR, anti-virus, antibacterial / anti-inflammatory. It is an effective tool for cell biology research.

Source Inhibitors Raw Materials by Region

Inhibitors Raw Materials South Korea

Browse more categories

Viscosity Controlling Inorganic Bases Dye Fungicides Coating Agent Sesquiterpene Water Softener Antidementia Agents Antiparasitics Cosmetic Colorant



Complaint

Email:

Message:

Send Message

Related News

Inhibitors

17-DMAG

5,5′-(2,5-Furandiyl)bis[2-thiophenemethanol]

Zotarolimus

Ispinesib

2-(Difluoromethyl)-1-(4,6-di-4-morpholinyl-1,3,5-triazin-2-yl)-1H-benzimidazole

A66

Crenolanib

N-[4-[[6-Methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenyl]benzamide

1,1′-[1,4-Phenylenebis(methylene)]bis[1,4,8,11-tetraazacyclotetradecane] hydrochloride (1:8)

N-[4-[1-(1,4-Dioxaspiro[4.5]dec-8-yl)-4-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl]phenyl]-N'-methylurea

Source Inhibitors Raw Materials by Region

Browse more categories