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Home > Biochemical Engineering > Inhibitors (Find 1083 items)

Inhibitors

Baricitinib

(1187594-09-7)
Baricitinib is a JAK1 and JAK2 inhibitor and have been used as a promising treatment for rheumatoid arthritis.

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Flupirtine maleate

(75507-68-5)
Analgesic. Substituted pyridine with central analgesic properties.

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Trelagliptin

(865759-25-7)
Trelagliptin(SYR-472) is a long acting dipeptidyl peptidase-4 (DPP-4) inhibitor that is being developed for the treatment of type 2 diabetes (T2D). IC50 value:Target: DPP4Two Phase II clinical studies have been completed with Efficacy and Safety of SYR-472 in Subjects With Type 2 Diabetes Mellitus. Phase III clinical studies with trelagliptin in Japan to evaluate its safety and efficacy in a once-weekly oral treatment regimen. Currently, all available DPP-4 inhibitors are dosed once-dail

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Pomalidomide

(19171-19-8)
Pomalidomide inhibits LPS-induced TNF-α release with IC50 of 13 nM

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Telaprevir

(402957-28-2)
A labelled peptidomimetic inhibitor of hepatitis C virus protease.

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Nitenpyram

(150824-47-8)
Nitenpyram is a chloronicotinyl insecticide; orally administered flea adulticide. Nitenpyram is used as an ectoparasiticide.

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Tropisetron hydrochloride

(105826-92-4)
Specific serotonin (5-HT3) receptor antagonist. Antiemetic.

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Ropinirole hydrochloride

(91374-20-8)
antiparkinsonian;non-ergoline D2, D3, and D4 dopamine receptor agonist with highest affinity for D3

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Small molecule inhibitors are a type of molecules that can interact with proteins and reduce the biological activity of target proteins, including enzyme inhibitors, transcription factor inhibitors, and ion channel blockers. It acts on popular signaling pathways, popular targets and popular research fields: MAPK, PI3K, JAK / STAT and other signaling pathways, HDAC, Aurora kinase, CDK and cell cycle regulators, integrase / protease, etc. Research fields such as epigenetics, CNS, GPCR, anti-virus, antibacterial / anti-inflammatory. It is an effective tool for cell biology research.

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