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Home > Biochemical Engineering > Inhibitors (Find 1083 items)

Inhibitors

(-)-Pimecrolimus

(137071-32-0)
Pimecrolimus caused a strong and dose-dependent inhibition of anti-IgE–induced release of histamine from mast cells and basophils (maximally 73% and 82%, respectively, at 500 nmol/L pimecrolimus) and of mast cell tryptase (maximally 75%) and a less pronou

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Brimonidine tartrate

(70359-46-5)
Used to treat open-angle glaucoma or ocular hypertension

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Solifenacin succinate

(242478-38-2)
Solifenacin succinate is a urinary antispasmodic of the antimuscarinic class.

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Cinacalcet hydrochloride

(364782-34-3)
The (R) enantiomer of Cinacalcet. Used in clinical trial in secondary hyperparathyroidism.

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Rasagiline mesylate

(161735-79-1)
Rasagiline is a selective irreversible MAO-B inhibitor. Rasagiline is an Antiparkinsonian agent.

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Dexmedetomidine hydrochloride

(145108-58-3)
highly selective, potent α2-adrenoceptor agonist, analgesic, anxiolytic, bradycardic, hypotensive, sedative, hypothermic

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Nafamostat

(81525-10-2)
Non-peptide synthetic protease inhibitors have a broad spectrum of strong enzyme inhibition. For the treatment of acute pancreatitis. It can improve the acute symptoms of acute pancreatitis, acute exacerbation of chronic pancreatitis, and post-traumatic pancreatitis.

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Ledipasvir

(1256388-51-8)
ChEBI: A benzimidazole derivative that is used in combination with sofosbuvir (under the trade name Harvoni) for the treatment of chronic hepatitis C genotype 1 infection.

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Carfilzomib

(868540-17-4)
Carfilzomib is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.

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Small molecule inhibitors are a type of molecules that can interact with proteins and reduce the biological activity of target proteins, including enzyme inhibitors, transcription factor inhibitors, and ion channel blockers. It acts on popular signaling pathways, popular targets and popular research fields: MAPK, PI3K, JAK / STAT and other signaling pathways, HDAC, Aurora kinase, CDK and cell cycle regulators, integrase / protease, etc. Research fields such as epigenetics, CNS, GPCR, anti-virus, antibacterial / anti-inflammatory. It is an effective tool for cell biology research.

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