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Home > Biochemical Engineering > Inhibitors (Find 1083 items)

Inhibitors

MPI-0479605

(1246529-32-7)
MPI-0479605 is a potent and selective ATP-competitive inhibitor of Mps1, with an IC50 of 1.8 nM.

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MLN0905

(1228960-69-7)
MLN0905 is a potent PLK1 inhibitor, with an IC50 of 2 nM.

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CAY10683 (SantacruzaMate A)

(1477949-42-0)
Santacruzamate A is a potent and selective histone deacetylase inhibitor.

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HS-173

(1276110-06-5)
HS-173 is a novel PI3K inhibitor, that is used for cancer treatment.

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K-Ras inhibitor

(1469338-01-9)
6H05 is a selective, and allosteric inhibitor of oncogenic mutant K-Ras(G12C). IC50 value:Target: K-Ras G12C6H05 gives the greatest degree of modification, which allosterically modifies the oncogenic G12C mutant of highly homologous protein H-Ras without affecting wild-type K-Ras [1]. 6H05 can be used as an intermediate for the synthesis of other oncogenic K-Ras(G12C) inhibitors [2].

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Small molecule inhibitors are a type of molecules that can interact with proteins and reduce the biological activity of target proteins, including enzyme inhibitors, transcription factor inhibitors, and ion channel blockers. It acts on popular signaling pathways, popular targets and popular research fields: MAPK, PI3K, JAK / STAT and other signaling pathways, HDAC, Aurora kinase, CDK and cell cycle regulators, integrase / protease, etc. Research fields such as epigenetics, CNS, GPCR, anti-virus, antibacterial / anti-inflammatory. It is an effective tool for cell biology research.

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